YM155 inhibits retinal pigment epithelium cell survival through EGFR/MAPK signaling pathway

YM155 inhibits retinal pigment epithelium cell survival through EGFR/MAPK signaling pathway

AIM: To investigate YM155's effect on retinal pigment epithelium (RPE) cells' viability and the potential regulatory mechanisms. METHODS: Human immortalized RPE cell lines (ARPE-19 cell line) were processed with YM155 and epidermal growth factor (EGF). ARPE-19 cell viability was detected b...

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Bibliographic Details
Main Authors:	Teng Li, Hong-Bing Zhang, Jia-Min Meng, Bo Yuan, Wen-Juan Lin, Yue Feng, Xiao-Dong Chen
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2021-04-01
Series:	International Journal of Ophthalmology
Subjects:	ym155 retinal pigment epithelial cell epidermal growth factor receptor mitogen-activated protein kinase
Online Access:	http://ies.ijo.cn/en_publish/2021/4/20210402.pdf

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