Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections

Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections

ABSTRACT The coronavirus disease 2019, COVID-19, is a complex disease with a wide range of symptoms from asymptomatic infections to severe acute respiratory syndrome with lethal outcome. Individual factors such as age, sex, and comorbidities increase the risk for severe infections, but other aspects...

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Bibliographic Details
Main Authors: Ebba Rosendal, Ionut Sebastian Mihai, Miriam Becker, Debojyoti Das, Lars Frängsmyr, B. David Persson, Gregory D. Rankin, Remigius Gröning, Johan Trygg, Mattias Forsell, Johan Ankarklev, Anders Blomberg, Johan Henriksson, Anna K. Överby, Annasara Lenman
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
SARS-CoV-2
COVID-19
TMPRSS2
serpin
alpha-1-antitrypsin
A1AT
Online Access:https://journals.asm.org/doi/10.1128/mbio.00892-22

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