Integrated Multi-Omic Analysis Reveals Immunosuppressive Phenotype Associated with Poor Outcomes in High-Grade Serous Ovarian Cancer

Integrated Multi-Omic Analysis Reveals Immunosuppressive Phenotype Associated with Poor Outcomes in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is characterized by a complex genomic landscape, with both genetic and epigenetic diversity contributing to its pathogenesis, disease course, and response to treatment. To better understand the association between genomic features and response to treatment am...

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Bibliographic Details
Main Authors: Russell Keathley, Masha Kocherginsky, Ramana Davuluri, Daniela Matei
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
high-grade serous ovarian cancer (HGSOC)
multi-omic analysis
data integration
consensus clustering
neural network
Online Access:https://www.mdpi.com/2072-6694/15/14/3649

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