PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE
The development of new implantable materials for bone regeneration remains a challenging task that is currently being considered from the perspective of tissue engineering. Such products should consist of bioactive threedimensional matrix containing either cells or biologically active proteins, incl...
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Format: | Article |
Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2020-11-01
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Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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Online Access: | https://vestnik.reaviz.ru/jour/article/view/49 |
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author | Yu. V. Ponomareva M. N. Milyakova N. N. Sarbaeva A. E. Atrashkova A. A. Supilnikov V. A. Vankov |
author_facet | Yu. V. Ponomareva M. N. Milyakova N. N. Sarbaeva A. E. Atrashkova A. A. Supilnikov V. A. Vankov |
author_sort | Yu. V. Ponomareva |
collection | DOAJ |
description | The development of new implantable materials for bone regeneration remains a challenging task that is currently being considered from the perspective of tissue engineering. Such products should consist of bioactive threedimensional matrix containing either cells or biologically active proteins, including growth factors, signaling molecules, or specific genes and/or their products. The paper presents a fragment of results obtained within studies on technology of creation and ways to achieve significant qualitative and quantitative parameters of such a matrix and studies evaluating biocompatibility in vivo using the original model of a critical bone defect. |
first_indexed | 2024-03-12T03:43:14Z |
format | Article |
id | doaj.art-149c674816b74effb0ad5646807ce066 |
institution | Directory Open Access Journal |
issn | 2226-762X 2782-1579 |
language | Russian |
last_indexed | 2024-03-12T03:43:14Z |
publishDate | 2020-11-01 |
publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
record_format | Article |
series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
spelling | doaj.art-149c674816b74effb0ad5646807ce0662023-09-03T12:58:30ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792020-11-010351446PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUEYu. V. Ponomareva0M. N. Milyakova1N. N. Sarbaeva2A. E. Atrashkova3A. A. Supilnikov4V. A. Vankov5Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииThe development of new implantable materials for bone regeneration remains a challenging task that is currently being considered from the perspective of tissue engineering. Such products should consist of bioactive threedimensional matrix containing either cells or biologically active proteins, including growth factors, signaling molecules, or specific genes and/or their products. The paper presents a fragment of results obtained within studies on technology of creation and ways to achieve significant qualitative and quantitative parameters of such a matrix and studies evaluating biocompatibility in vivo using the original model of a critical bone defect.https://vestnik.reaviz.ru/jour/article/view/49децеллюляризациякостный матриксостеорегенерациябиосовместимость. |
spellingShingle | Yu. V. Ponomareva M. N. Milyakova N. N. Sarbaeva A. E. Atrashkova A. A. Supilnikov V. A. Vankov PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье децеллюляризация костный матрикс остеорегенерация биосовместимость. |
title | PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE |
title_full | PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE |
title_fullStr | PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE |
title_full_unstemmed | PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE |
title_short | PRODUCTION AND BIOCOMPATIBILITY EVALUATION OF A THREE-DIMENSIONAL BIOACTIVE MATRIX WITH SPECIFIED PROPERTIES BASED ON DECELLULARIZED HETEROLOGOUS BONE TISSUE |
title_sort | production and biocompatibility evaluation of a three dimensional bioactive matrix with specified properties based on decellularized heterologous bone tissue |
topic | децеллюляризация костный матрикс остеорегенерация биосовместимость. |
url | https://vestnik.reaviz.ru/jour/article/view/49 |
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