Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension
Introduction: Recent developments in echocardiography made assessing pulmonary arterial hypertension (PAH) in the heart, a suitable choice. This study aimed to investigate the association of myocardial right ventricular relaxation time and systolic pulmonary artery pressure (SPAP) in PAH patients.Ma...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2023-06-01
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| Series: | Journal of Cardio-Thoracic Medicine |
| Subjects: | |
| Online Access: | https://jctm.mums.ac.ir/article_22673_e8a6ccd2458dada11b072d4738618c61.pdf |
| _version_ | 1797784810606821376 |
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| author | Feraeshteh Ghaderi Zahra Abbasi shaye Farveh vakilian Sara Afshar Vafa Baradaran Rahimi |
| author_facet | Feraeshteh Ghaderi Zahra Abbasi shaye Farveh vakilian Sara Afshar Vafa Baradaran Rahimi |
| author_sort | Feraeshteh Ghaderi |
| collection | DOAJ |
| description | Introduction: Recent developments in echocardiography made assessing pulmonary arterial hypertension (PAH) in the heart, a suitable choice. This study aimed to investigate the association of myocardial right ventricular relaxation time and systolic pulmonary artery pressure (SPAP) in PAH patients.Materials and Methods: The present study evaluated 74 patients with PAH (n=49) and age- and sex-matched healthy controls (n=25). All patients underwent transthoracic echocardiography. We evaluated the right ventricular (RV) function's echocardiographic parameters, including IVRT, IVCT, S, E, A, S’, E’, A’, ET, DT, TAPSE, FAC, and SPAP.Results: We found no significant differences in age and gender between the two studied groups (p>0.05). However, we observed a significant difference in IVRT, IVCT, E’, A’ (p=0.004), A, S’, DT, TAPSE, FAC and SPSP (p<0.001 for all cases) between two studied groups. Unlike the control group, we revealed a significant correlation between S’ and E’ (r=0.45, p=<0.001), S’ and A’ (r=0.66, p=<0.001), S’ and FAC (r=0.3, p=0.035), A and A’(r=0.4, p=0.004), TAPSE and FAC (r=0.82, p=<0.001), TAPSE and SPAP (r= -0.43, p=0.002), MPI and A (r= -0.35, p=0.013), MPI and ET (r= -0.72, p=<0.001), E/A and E/E’(r=0.47, p=<0.001), and BSA and S’ (r= -0.3, p=0.011). In addition, no meaningful association was found between SPAP and IVRT and IVCT (p>0.05).Conclusion: Our findings revealed that IVRT and IVCT might not be affected by the SPAP and, therefore, could be used in the assessment of right ventricular function in patients with PAH. |
| first_indexed | 2024-03-13T00:45:11Z |
| format | Article |
| id | doaj.art-14a3e0a1979749cc99d14480ff098dbd |
| institution | Directory Open Access Journal |
| issn | 2345-2447 2322-5750 |
| language | English |
| last_indexed | 2024-03-13T00:45:11Z |
| publishDate | 2023-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardio-Thoracic Medicine |
| spelling | doaj.art-14a3e0a1979749cc99d14480ff098dbd2023-07-09T06:51:58ZengMashhad University of Medical SciencesJournal of Cardio-Thoracic Medicine2345-24472322-57502023-06-011121141115010.22038/jctm.2023.72563.142122673Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial HypertensionFeraeshteh Ghaderi0Zahra Abbasi shaye1Farveh vakilian2Sara Afshar3Vafa Baradaran Rahimi4Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Akbar Clinical Research and Development Unit, Mashhad University of Medical Sciences, Mashhad, Iran.Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Recent developments in echocardiography made assessing pulmonary arterial hypertension (PAH) in the heart, a suitable choice. This study aimed to investigate the association of myocardial right ventricular relaxation time and systolic pulmonary artery pressure (SPAP) in PAH patients.Materials and Methods: The present study evaluated 74 patients with PAH (n=49) and age- and sex-matched healthy controls (n=25). All patients underwent transthoracic echocardiography. We evaluated the right ventricular (RV) function's echocardiographic parameters, including IVRT, IVCT, S, E, A, S’, E’, A’, ET, DT, TAPSE, FAC, and SPAP.Results: We found no significant differences in age and gender between the two studied groups (p>0.05). However, we observed a significant difference in IVRT, IVCT, E’, A’ (p=0.004), A, S’, DT, TAPSE, FAC and SPSP (p<0.001 for all cases) between two studied groups. Unlike the control group, we revealed a significant correlation between S’ and E’ (r=0.45, p=<0.001), S’ and A’ (r=0.66, p=<0.001), S’ and FAC (r=0.3, p=0.035), A and A’(r=0.4, p=0.004), TAPSE and FAC (r=0.82, p=<0.001), TAPSE and SPAP (r= -0.43, p=0.002), MPI and A (r= -0.35, p=0.013), MPI and ET (r= -0.72, p=<0.001), E/A and E/E’(r=0.47, p=<0.001), and BSA and S’ (r= -0.3, p=0.011). In addition, no meaningful association was found between SPAP and IVRT and IVCT (p>0.05).Conclusion: Our findings revealed that IVRT and IVCT might not be affected by the SPAP and, therefore, could be used in the assessment of right ventricular function in patients with PAH.https://jctm.mums.ac.ir/article_22673_e8a6ccd2458dada11b072d4738618c61.pdfmyocardial right ventricular relaxation timepulmonary artery pressurepulmonary arterial hypertension |
| spellingShingle | Feraeshteh Ghaderi Zahra Abbasi shaye Farveh vakilian Sara Afshar Vafa Baradaran Rahimi Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension Journal of Cardio-Thoracic Medicine myocardial right ventricular relaxation time pulmonary artery pressure pulmonary arterial hypertension |
| title | Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension |
| title_full | Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension |
| title_fullStr | Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension |
| title_full_unstemmed | Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension |
| title_short | Relationship between Myocardial Right Ventricular Relaxation Time and Pulmonary Artery Pressure in Patients with Pulmonary Arterial Hypertension |
| title_sort | relationship between myocardial right ventricular relaxation time and pulmonary artery pressure in patients with pulmonary arterial hypertension |
| topic | myocardial right ventricular relaxation time pulmonary artery pressure pulmonary arterial hypertension |
| url | https://jctm.mums.ac.ir/article_22673_e8a6ccd2458dada11b072d4738618c61.pdf |
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