PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial–Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro

PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial–Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro

Metastasis accounts for the vast majority of deaths in breast cancer, and novel and effective treatments to inhibit cancer metastasis remain urgently developed. The expression level of heat shock protein 90 (HSP90) in invasive breast cancer tissue is higher than in adjacent non-cancerous tissue. In...

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Bibliographic Details
Main Authors: Aotong Zhang, Xin Qi, Fu Du, Guojian Zhang, Dehai Li, Jing Li
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Marine Drugs
Subjects:
HSP90
inhibitor
EMT
metastasis
breast cancer
Online Access:https://www.mdpi.com/1660-3397/19/2/117

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