Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding

Aim: The aim of this study was to investigate the place of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal vaginal bleeding. Methods: In this study, we retrospectively evaluated hospital records of 380 patients who had undergone endometrial biopsy with the...

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Main Authors: Onur Kaya, Cem Dane, Ecem Kaya, Mehmet Murat Semiz, Ahmet Çetin, Gamze Saygı
Format: Article
Language:English
Published: Galenos Yayinevi 2014-09-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access:http://www.hasekidergisi.com/article_7270/Predictive-Value-Of-Endometrial-Thickness-In-Detecting-Endometrial-Malignancy-In-Patients-With-Postmenopausal-Bleeding
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author Onur Kaya
Cem Dane
Ecem Kaya
Mehmet Murat Semiz
Ahmet Çetin
Gamze Saygı
author_facet Onur Kaya
Cem Dane
Ecem Kaya
Mehmet Murat Semiz
Ahmet Çetin
Gamze Saygı
author_sort Onur Kaya
collection DOAJ
description Aim: The aim of this study was to investigate the place of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal vaginal bleeding. Methods: In this study, we retrospectively evaluated hospital records of 380 patients who had undergone endometrial biopsy with the diagnosis of postmenopausal bleeding in the Department of Obstetrics and Gynecology at Haseki Training and Research Hospital between January 2008 and January 2012. Results: Analysis of the biopsy specimens revealed benign or premalignant endometrium in 355 of the 380 patients who were histopathologically diagnosed with postmenopausal bleeding. The mean endometrial thickness in 25 patient with malign endometrium was 11.6±8.2 mm. In our study, when a endometrial thickness cut-off value of 10.8 mm was taken, the sensitivity, specificity, and negative predictive value was found to be 84%, 52%, and 96%, respectively. Conclusion: In our study, almost all patients (96%) with endometrial thickness of less than 10.8 mm, were free from endometrial malignancy. (The Me­di­cal Bul­le­tin of Ha­se­ki 2014; 52:164-7)
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spelling doaj.art-14a68aab256446b98da20d3da37ef2602023-02-15T16:14:31ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882014-09-0152316416710.4274/haseki.1633Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal BleedingOnur Kaya0Cem Dane1Ecem Kaya2Mehmet Murat Semiz3Ahmet Çetin4Gamze Saygı5Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, TürkiyeHaseki Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, TürkiyeHaseki Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, TürkiyeHaseki Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, TürkiyeHaseki Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, TürkiyeHaseki Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, İstanbul, TürkiyeAim: The aim of this study was to investigate the place of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal vaginal bleeding. Methods: In this study, we retrospectively evaluated hospital records of 380 patients who had undergone endometrial biopsy with the diagnosis of postmenopausal bleeding in the Department of Obstetrics and Gynecology at Haseki Training and Research Hospital between January 2008 and January 2012. Results: Analysis of the biopsy specimens revealed benign or premalignant endometrium in 355 of the 380 patients who were histopathologically diagnosed with postmenopausal bleeding. The mean endometrial thickness in 25 patient with malign endometrium was 11.6±8.2 mm. In our study, when a endometrial thickness cut-off value of 10.8 mm was taken, the sensitivity, specificity, and negative predictive value was found to be 84%, 52%, and 96%, respectively. Conclusion: In our study, almost all patients (96%) with endometrial thickness of less than 10.8 mm, were free from endometrial malignancy. (The Me­di­cal Bul­le­tin of Ha­se­ki 2014; 52:164-7)http://www.hasekidergisi.com/article_7270/Predictive-Value-Of-Endometrial-Thickness-In-Detecting-Endometrial-Malignancy-In-Patients-With-Postmenopausal-BleedingPostmenapousal bleedingendometrial thicknesstransvaginal ultrasonography
spellingShingle Onur Kaya
Cem Dane
Ecem Kaya
Mehmet Murat Semiz
Ahmet Çetin
Gamze Saygı
Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
Haseki Tıp Bülteni
Postmenapousal bleeding
endometrial thickness
transvaginal ultrasonography
title Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
title_full Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
title_fullStr Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
title_full_unstemmed Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
title_short Predictive Value of Endometrial Thickness in Detecting Endometrial Malignancy in Patients with Postmenopausal Bleeding
title_sort predictive value of endometrial thickness in detecting endometrial malignancy in patients with postmenopausal bleeding
topic Postmenapousal bleeding
endometrial thickness
transvaginal ultrasonography
url http://www.hasekidergisi.com/article_7270/Predictive-Value-Of-Endometrial-Thickness-In-Detecting-Endometrial-Malignancy-In-Patients-With-Postmenopausal-Bleeding
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AT ecemkaya predictivevalueofendometrialthicknessindetectingendometrialmalignancyinpatientswithpostmenopausalbleeding
AT mehmetmuratsemiz predictivevalueofendometrialthicknessindetectingendometrialmalignancyinpatientswithpostmenopausalbleeding
AT ahmetcetin predictivevalueofendometrialthicknessindetectingendometrialmalignancyinpatientswithpostmenopausalbleeding
AT gamzesaygı predictivevalueofendometrialthicknessindetectingendometrialmalignancyinpatientswithpostmenopausalbleeding