Intravitreal gas injection for the treatment of diabetic macular edema
Dominic McHugh, Bhaskar Gupta, Manzar Saeed King's College Hospital, Denmark Hill, London, England, UK Purpose: This study investigates the efficacy of an intravitreal gas injection in inducing a posterior vitreous detachment (PVD) in patients with clinically significant diabetic macular...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2011-10-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/intravitreal-gas-injection-for-the-treatment-of-diabetic-macular-edema-a8548 |
| _version_ | 1818695513515491328 |
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| author | McHugh D Gupta B Saeed M |
| author_facet | McHugh D Gupta B Saeed M |
| author_sort | McHugh D |
| collection | DOAJ |
| description | Dominic McHugh, Bhaskar Gupta, Manzar Saeed King's College Hospital, Denmark Hill, London, England, UK Purpose: This study investigates the efficacy of an intravitreal gas injection in inducing a posterior vitreous detachment (PVD) in patients with clinically significant diabetic macular edema refractory to laser therapy. Methods: A local ethics committee-approved technique of an intravitreal injection of pure perfluoropropane gas (C3F8) was performed for all participants. After a period of prone positioning, the patients underwent regular and detailed clinical review. Main outcome measures: The induction of a PVD, change in macular thickness, change in visual acuity. Results: A PVD was induced in all five eyes with subsequent signs of reduction in macular thickness and resolution of exudates. Mean visual improvement was 11 ETDRS (Early Treatment Diabetic Retinopathy Study) letters (range 4–21). Apart from a transient vitreous hemorrhage in one eye, there were no significant treatment-related complications. Conclusion: The induction of a PVD by pneumatic retinopexy appears to have a significant influence on diabetic macular edema in eyes which have not successfully responded to macular laser therapy. A randomized clinical trial is justified on the basis of the initial promising data. Keywords: optical coherence tomography, OCT, posterior vitreous detachment, perfluoropropane |
| first_indexed | 2024-12-17T13:46:40Z |
| format | Article |
| id | doaj.art-14a924cabdb049f382559168205489d6 |
| institution | Directory Open Access Journal |
| issn | 1177-5467 1177-5483 |
| language | English |
| last_indexed | 2024-12-17T13:46:40Z |
| publishDate | 2011-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-14a924cabdb049f382559168205489d62022-12-21T21:46:08ZengDove Medical PressClinical Ophthalmology1177-54671177-54832011-10-012011default15431548Intravitreal gas injection for the treatment of diabetic macular edemaMcHugh DGupta BSaeed MDominic McHugh, Bhaskar Gupta, Manzar Saeed King's College Hospital, Denmark Hill, London, England, UK Purpose: This study investigates the efficacy of an intravitreal gas injection in inducing a posterior vitreous detachment (PVD) in patients with clinically significant diabetic macular edema refractory to laser therapy. Methods: A local ethics committee-approved technique of an intravitreal injection of pure perfluoropropane gas (C3F8) was performed for all participants. After a period of prone positioning, the patients underwent regular and detailed clinical review. Main outcome measures: The induction of a PVD, change in macular thickness, change in visual acuity. Results: A PVD was induced in all five eyes with subsequent signs of reduction in macular thickness and resolution of exudates. Mean visual improvement was 11 ETDRS (Early Treatment Diabetic Retinopathy Study) letters (range 4–21). Apart from a transient vitreous hemorrhage in one eye, there were no significant treatment-related complications. Conclusion: The induction of a PVD by pneumatic retinopexy appears to have a significant influence on diabetic macular edema in eyes which have not successfully responded to macular laser therapy. A randomized clinical trial is justified on the basis of the initial promising data. Keywords: optical coherence tomography, OCT, posterior vitreous detachment, perfluoropropanehttp://www.dovepress.com/intravitreal-gas-injection-for-the-treatment-of-diabetic-macular-edema-a8548 |
| spellingShingle | McHugh D Gupta B Saeed M Intravitreal gas injection for the treatment of diabetic macular edema Clinical Ophthalmology |
| title | Intravitreal gas injection for the treatment of diabetic macular edema |
| title_full | Intravitreal gas injection for the treatment of diabetic macular edema |
| title_fullStr | Intravitreal gas injection for the treatment of diabetic macular edema |
| title_full_unstemmed | Intravitreal gas injection for the treatment of diabetic macular edema |
| title_short | Intravitreal gas injection for the treatment of diabetic macular edema |
| title_sort | intravitreal gas injection for the treatment of diabetic macular edema |
| url | http://www.dovepress.com/intravitreal-gas-injection-for-the-treatment-of-diabetic-macular-edema-a8548 |
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