A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection

A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection

Aortic dissection (AD) is a fatal cardiovascular disease with limited pharmacotherapies. To discover novel therapeutic targets for AD, the present study was conducted on ascending aorta samples from AD patients versus those from control subjects using proteomic analysis. Integrated proteomic data an...

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Bibliographic Details
Main Authors: Hui Jiang, Yaping Zhao, Meiming Su, Lu Sun, Meijie Chen, Zhidan Zhang, Iqra Ilyas, Zhihua Wang, Peter J. Little, Li Wang, Jianping Weng, Jianjun Ge, Suowen Xu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Pharmacological Research
Subjects:
S100A8
S100A9
Aortic dissection
Pharmacotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003857

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