Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases

Mitochondrial ferritin (FtMt) is a novel iron-storage protein in mitochondria. Evidences have shown that FtMt is structurally and functionally similar to the cytosolic H-chain ferritin. It protects mitochondria from iron-induced oxidative damage presumably through sequestration of potentially harmfu...

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Bibliographic Details
Main Authors: Guofen eGao, Yan-Zhong eChang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00019/full