Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways

Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways

The precise pathogenic mechanism in Cu exposure-cause nephrotoxicity remains unclear. This study investigated the underlying molecular mechanism of copper sulfate (CuSO<sub>4</sub>)-induced nephrotoxicity. Mice were treated with CuSO<sub>4</sub> at 50, 100, 200 mg/kg/day or c...

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Bibliographic Details
Main Authors: Chongshan Dai, Qiangqiang Liu, Daowen Li, Gaurav Sharma, Jianli Xiong, Xilong Xiao
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
copper
oxidative stress
apoptosis
endoplasmic reticulum stress
kidney
cytotoxicity
Online Access:https://www.mdpi.com/2218-273X/10/7/1010

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