Application of microneedle-based vaccines in biosecurity
Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats. Vaccination is one of the most effective means for countries to maintain biosecurity and respond to bioterrorism attacks...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2022-06-01
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| Series: | Journal of Biosafety and Biosecurity |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258893382200005X |
| _version_ | 1818533880804671488 |
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| author | Zhiying Jin Baohua Zhao Wei Wan Yue Li Xuexin Bai Chenyi Hu Jing Wang Yanwei Li Wenwen Xin Lin Kang Hao Yang Jinglin Wang Shan Gao |
| author_facet | Zhiying Jin Baohua Zhao Wei Wan Yue Li Xuexin Bai Chenyi Hu Jing Wang Yanwei Li Wenwen Xin Lin Kang Hao Yang Jinglin Wang Shan Gao |
| author_sort | Zhiying Jin |
| collection | DOAJ |
| description | Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats. Vaccination is one of the most effective means for countries to maintain biosecurity and respond to bioterrorism attacks. Microneedles are emerging as a potential vaccine delivery method with minimal pain, no bleeding, and the ability to be self-administered, doing away with the need for professional health care workers. This last advantage, particularly if combined with room temperature preservation, could have an important role in improving national biosecurity through large-scale, rapid deployment of a biological vaccine. In this review, we summarized the research status of microneedles, including the types, materials, and production technologies of microneedles. Recent progress regarding microneedles in the field of biosecurity is introduced and challenges in its future application are discussed. |
| first_indexed | 2024-12-11T18:04:34Z |
| format | Article |
| id | doaj.art-14b3308c45be45e08cebfdee71faee7f |
| institution | Directory Open Access Journal |
| issn | 2588-9338 |
| language | English |
| last_indexed | 2024-12-11T18:04:34Z |
| publishDate | 2022-06-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Biosafety and Biosecurity |
| spelling | doaj.art-14b3308c45be45e08cebfdee71faee7f2022-12-22T00:55:47ZengKeAi Communications Co., Ltd.Journal of Biosafety and Biosecurity2588-93382022-06-01417583Application of microneedle-based vaccines in biosecurityZhiying Jin0Baohua Zhao1Wei Wan2Yue Li3Xuexin Bai4Chenyi Hu5Jing Wang6Yanwei Li7Wenwen Xin8Lin Kang9Hao Yang10Jinglin Wang11Shan Gao12State Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, China; Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, ChinaHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, ChinaState Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, China; Corresponding authors.State Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, China; Corresponding authors.State Key Laboratory of Pathogens and Biosecurity, Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, China; Corresponding authors.Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats. Vaccination is one of the most effective means for countries to maintain biosecurity and respond to bioterrorism attacks. Microneedles are emerging as a potential vaccine delivery method with minimal pain, no bleeding, and the ability to be self-administered, doing away with the need for professional health care workers. This last advantage, particularly if combined with room temperature preservation, could have an important role in improving national biosecurity through large-scale, rapid deployment of a biological vaccine. In this review, we summarized the research status of microneedles, including the types, materials, and production technologies of microneedles. Recent progress regarding microneedles in the field of biosecurity is introduced and challenges in its future application are discussed.http://www.sciencedirect.com/science/article/pii/S258893382200005XMicroneedleVaccineTransdermal deliveryBiosecurity |
| spellingShingle | Zhiying Jin Baohua Zhao Wei Wan Yue Li Xuexin Bai Chenyi Hu Jing Wang Yanwei Li Wenwen Xin Lin Kang Hao Yang Jinglin Wang Shan Gao Application of microneedle-based vaccines in biosecurity Journal of Biosafety and Biosecurity Microneedle Vaccine Transdermal delivery Biosecurity |
| title | Application of microneedle-based vaccines in biosecurity |
| title_full | Application of microneedle-based vaccines in biosecurity |
| title_fullStr | Application of microneedle-based vaccines in biosecurity |
| title_full_unstemmed | Application of microneedle-based vaccines in biosecurity |
| title_short | Application of microneedle-based vaccines in biosecurity |
| title_sort | application of microneedle based vaccines in biosecurity |
| topic | Microneedle Vaccine Transdermal delivery Biosecurity |
| url | http://www.sciencedirect.com/science/article/pii/S258893382200005X |
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