POTENTIAL USAGE OF NK CELLS AND NKG2D-POSITIVE LYMPHOCYTES AS TARGETS IN THERAPY OF CROHN’S DISEASE

POTENTIAL USAGE OF NK CELLS AND NKG2D-POSITIVE LYMPHOCYTES AS TARGETS IN THERAPY OF CROHN’S DISEASE

Autoimmune mechanisms of Crohn’s disease have been extensively  studied, following discovery of NOD2, ATG16L1, IRGM genetic  polymorphisms associated with  Crohn’s disease.  These  genes play an important role  in  innate immune response  against  intracellular bacteria, in  particular, due  to  the...

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Bibliographic Details
Main Authors: E. A. Shulenina, E. V. Abakushina, E. Yu. Lyssuk
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2017-08-01
Series:Медицинская иммунология
Subjects:
nkg2d
nk
mica
macrophages
autoimmunity
crohn’s disease
Online Access:https://www.mimmun.ru/mimmun/article/view/1317

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