The Role of Bioactive Small Molecules in COPD Pathogenesis
Chronic obstructive pulmonary disease (COPD) is recognized as a predominant contributor to mortality worldwide, which causes significant burdens to both society and individuals. Given the limited treatment options for COPD, there lies a critical realization: the imperative for expeditious developmen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Series: | COPD |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/15412555.2024.2307618 |
| _version_ | 1826920190901747712 |
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| author | Sha Liao Yahong Chen |
| author_facet | Sha Liao Yahong Chen |
| author_sort | Sha Liao |
| collection | DOAJ |
| description | Chronic obstructive pulmonary disease (COPD) is recognized as a predominant contributor to mortality worldwide, which causes significant burdens to both society and individuals. Given the limited treatment options for COPD, there lies a critical realization: the imperative for expeditious development of novel therapeutic modalities that can effectively alleviate disease progression and enhance the quality of life experienced by COPD patients. Within the intricate field of COPD pathogenesis, an assortment of biologically active small molecules, encompassing small protein molecules and their derivatives, assumes crucial roles through diverse mechanisms. These mechanisms relate to the regulation of redox balance, the inhibition of the release of inflammatory mediators, and the modulation of cellular functions. Therefore, the present article aims to explore and elucidate the distinct roles played by different categories of biologically active small molecules in contributing to the pathogenesis of COPD. |
| first_indexed | 2024-03-08T04:16:13Z |
| format | Article |
| id | doaj.art-14b4c47f1c5043db93442c7919235a81 |
| institution | Directory Open Access Journal |
| issn | 1541-2555 1541-2563 |
| language | English |
| last_indexed | 2025-02-17T13:26:27Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | COPD |
| spelling | doaj.art-14b4c47f1c5043db93442c7919235a812024-12-26T08:50:44ZengTaylor & Francis GroupCOPD1541-25551541-25632024-12-0121110.1080/15412555.2024.2307618The Role of Bioactive Small Molecules in COPD PathogenesisSha Liao0Yahong Chen1Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, ChinaDepartment of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, ChinaChronic obstructive pulmonary disease (COPD) is recognized as a predominant contributor to mortality worldwide, which causes significant burdens to both society and individuals. Given the limited treatment options for COPD, there lies a critical realization: the imperative for expeditious development of novel therapeutic modalities that can effectively alleviate disease progression and enhance the quality of life experienced by COPD patients. Within the intricate field of COPD pathogenesis, an assortment of biologically active small molecules, encompassing small protein molecules and their derivatives, assumes crucial roles through diverse mechanisms. These mechanisms relate to the regulation of redox balance, the inhibition of the release of inflammatory mediators, and the modulation of cellular functions. Therefore, the present article aims to explore and elucidate the distinct roles played by different categories of biologically active small molecules in contributing to the pathogenesis of COPD.https://www.tandfonline.com/doi/10.1080/15412555.2024.2307618Bioactive small moleculesCOPDpathogenesis |
| spellingShingle | Sha Liao Yahong Chen The Role of Bioactive Small Molecules in COPD Pathogenesis COPD Bioactive small molecules COPD pathogenesis |
| title | The Role of Bioactive Small Molecules in COPD Pathogenesis |
| title_full | The Role of Bioactive Small Molecules in COPD Pathogenesis |
| title_fullStr | The Role of Bioactive Small Molecules in COPD Pathogenesis |
| title_full_unstemmed | The Role of Bioactive Small Molecules in COPD Pathogenesis |
| title_short | The Role of Bioactive Small Molecules in COPD Pathogenesis |
| title_sort | role of bioactive small molecules in copd pathogenesis |
| topic | Bioactive small molecules COPD pathogenesis |
| url | https://www.tandfonline.com/doi/10.1080/15412555.2024.2307618 |
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