Stretch-Induced Down-Regulation of HCN2 Suppresses Contractile Activity

Stretch-Induced Down-Regulation of HCN2 Suppresses Contractile Activity

Although hyperpolarization-activated and cyclic nucleotide-gated 2 channels (HCN2) are expressed in multiple cell types in the gut, the role of HCN2 in intestinal motility is poorly understood. HCN2 is down-regulated in intestinal smooth muscle in a rodent model of ileus. Thus, the purpose of this s...

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Bibliographic Details
Main Authors:	Job Baffin Kola, Botagoz Turarova, Dora Csige, Ádám Sipos, Luca Varga, Bence Gergely, Farah Al Refai, Iván P. Uray, Tibor Docsa, Karen Uray
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	Molecules
Subjects:	intestinal motility hyperpolarization-activated and cyclic nucleotide-gated 2 channel mechanotransduction ileus
Online Access:	https://www.mdpi.com/1420-3049/28/11/4359

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