Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review
Interest in electrochemical analysis of purine nucleobases and few other important purine derivatives has been growing rapidly. Over the period of the past decade, the design of electrochemical biosensors has been focused on achieving high sensitivity and efficiency. The range of existing electroche...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-01-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/15/1/1564 |
| _version_ | 1798006216651177984 |
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| author | Vimal Kumar Sharma Frantisek Jelen Libuse Trnkova |
| author_facet | Vimal Kumar Sharma Frantisek Jelen Libuse Trnkova |
| author_sort | Vimal Kumar Sharma |
| collection | DOAJ |
| description | Interest in electrochemical analysis of purine nucleobases and few other important purine derivatives has been growing rapidly. Over the period of the past decade, the design of electrochemical biosensors has been focused on achieving high sensitivity and efficiency. The range of existing electrochemical methods with carbon electrode displays the highest rate in the development of biosensors. Moreover, modification of electrode surfaces based on nanomaterials is frequently used due to their extraordinary conductivity and surface to volume ratio. Different strategies for modifying electrode surfaces facilitate electron transport between the electrode surface and biomolecules, including DNA, oligonucleotides and their components. This review aims to summarize recent developments in the electrochemical analysis of purine derivatives, as well as discuss different applications. |
| first_indexed | 2024-04-11T12:52:31Z |
| format | Article |
| id | doaj.art-14b7a9fe3e7e4b35abcbc8355c76d801 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T12:52:31Z |
| publishDate | 2015-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-14b7a9fe3e7e4b35abcbc8355c76d8012022-12-22T04:23:10ZengMDPI AGSensors1424-82202015-01-011511564160010.3390/s150101564s150101564Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A ReviewVimal Kumar Sharma0Frantisek Jelen1Libuse Trnkova2Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, CZ–625 00 Brno, Czech RepublicInstitute of Biophysics of the Academy of Sciences of the Czech Republic, V.V.I., Kralovopolska 135, CZ–612 65 Brno, Czech RepublicDepartment of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, CZ–625 00 Brno, Czech RepublicInterest in electrochemical analysis of purine nucleobases and few other important purine derivatives has been growing rapidly. Over the period of the past decade, the design of electrochemical biosensors has been focused on achieving high sensitivity and efficiency. The range of existing electrochemical methods with carbon electrode displays the highest rate in the development of biosensors. Moreover, modification of electrode surfaces based on nanomaterials is frequently used due to their extraordinary conductivity and surface to volume ratio. Different strategies for modifying electrode surfaces facilitate electron transport between the electrode surface and biomolecules, including DNA, oligonucleotides and their components. This review aims to summarize recent developments in the electrochemical analysis of purine derivatives, as well as discuss different applications.http://www.mdpi.com/1424-8220/15/1/1564purine derivativeselectrochemistry of purinescarbon electrodegold electrodeplatinum electrodeindium tin oxide electrodeboron doped electrodemodified electrodes |
| spellingShingle | Vimal Kumar Sharma Frantisek Jelen Libuse Trnkova Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review Sensors purine derivatives electrochemistry of purines carbon electrode gold electrode platinum electrode indium tin oxide electrode boron doped electrode modified electrodes |
| title | Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review |
| title_full | Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review |
| title_fullStr | Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review |
| title_full_unstemmed | Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review |
| title_short | Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review |
| title_sort | functionalized solid electrodes for electrochemical biosensing of purine nucleobases and their analogues a review |
| topic | purine derivatives electrochemistry of purines carbon electrode gold electrode platinum electrode indium tin oxide electrode boron doped electrode modified electrodes |
| url | http://www.mdpi.com/1424-8220/15/1/1564 |
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