Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats

Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats

Applying serotonergic (5-HT) agonists or grafting of fetal serotonergic cells into the spinal cord improves locomotion after spinal cord injury. Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT2 (Cyproheptadine; Cypr...

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Bibliographic Details
Main Authors: Henryk Majczyński, Anna M. Cabaj, Larry M. Jordan, Urszula Sławińska
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neural Circuits
Subjects:
serotonin
antagonist
inverse agonist
spinal cord
intrathecal application
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2020.00014/full

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