Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study
Abstract The current study aims to assess the prevalence of different genera of Rickettsiales, intracellular bacteria, in dogs across various regions of Iran. Rickettsiales, as zoonotic pathogens, can have various manifestations in different species, including immunosuppression, anaemia and neuropat...
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Veterinary Medicine and Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/vms3.1381 |
| _version_ | 1827197810699665408 |
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| author | Arman Abdous Mehdi Rahnama Farzane Shams Mohammad Jokar Vahid Rahmanian Mehran Farhoodi Aryan Abbassioun Mohammad Sadegh Kamjoo |
| author_facet | Arman Abdous Mehdi Rahnama Farzane Shams Mohammad Jokar Vahid Rahmanian Mehran Farhoodi Aryan Abbassioun Mohammad Sadegh Kamjoo |
| author_sort | Arman Abdous |
| collection | DOAJ |
| description | Abstract The current study aims to assess the prevalence of different genera of Rickettsiales, intracellular bacteria, in dogs across various regions of Iran. Rickettsiales, as zoonotic pathogens, can have various manifestations in different species, including immunosuppression, anaemia and neuropathy. Due to their close interactions with people and livestock, dogs can serve as reservoirs and transmit these pathogens to humans and other animals. The data from this research can be valuable for managing and controlling related diseases and complications in Iran and possibly neighbouring countries. Pertinent data for this study was gathered without time limitations until 1 March 2022, from different databases. Of all the inspected studies, 26 were eligible based on the inclusion criteria. The Egger test result and asymmetry in the funnel plot revealed significant publication bias; therefore, the meta‐analysis model was corrected with the trim‐and‐fill method. After correction, the prevalence of rickettsial infections among dogs varies by genus – 20.1% for Anaplasma spp. and 10% for Ehrlichia spp. – with an overall prevalence estimated at 18.3% by random‐effects analysis. The highest and lowest estimated pooled prevalences were associated with the southwestern (38.5%) and southern (0.3%) provinces of Iran, respectively. The pooled prevalence of rickettsial infection was higher in female dogs (OR = 1.198; p < 0.978; 95% CI, 0.842–1.705) and in dogs ≤2 years (OR = 1.014; p < 0.312; 95% CI, 0.598–1.72), but the difference was not statistically significant. Ultimately, the pooled prevalence of rickettsial infections among dogs is relatively low compared to other countries like Qatar, Iraq, Saudi Arabia and Turkey, which are nearby Iran. Given the significant clinical outcomes of this disease, necessary measures for prevention should be taken. |
| first_indexed | 2024-04-25T00:10:53Z |
| format | Article |
| id | doaj.art-14b94a705dba4502a7a54fa3ee31f057 |
| institution | Directory Open Access Journal |
| issn | 2053-1095 |
| language | English |
| last_indexed | 2025-03-21T10:07:03Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj.art-14b94a705dba4502a7a54fa3ee31f0572024-07-04T11:51:51ZengWileyVeterinary Medicine and Science2053-10952024-03-01102n/an/a10.1002/vms3.1381Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis studyArman Abdous0Mehdi Rahnama1Farzane Shams2Mohammad Jokar3Vahid Rahmanian4Mehran Farhoodi5Aryan Abbassioun6Mohammad Sadegh Kamjoo7Faculty of Veterinary Medicine Karaj Branch Islamic Azad University Karaj IranFaculty of Veterinary Medicine Science and Research Branch Islamic Azad University Tehran IranGraduate School for Cellular and Biomedical Sciences University of Bern Bern SwitzerlandFaculty of Veterinary Medicine Karaj Branch Islamic Azad University Karaj IranDepartment of Public Health Torbat Jam Faculty of Medical Sciences Torbat Jam IranDepartment of Clinical Sciences Faculty of Veterinary Medicine Karaj Branch Islamic Azad University Karaj IranDepartment of Virology Faculty of Veterinary Medicine Tehran University Tehran IranFaculty of Veterinary Medicine Karaj Branch Islamic Azad University Karaj IranAbstract The current study aims to assess the prevalence of different genera of Rickettsiales, intracellular bacteria, in dogs across various regions of Iran. Rickettsiales, as zoonotic pathogens, can have various manifestations in different species, including immunosuppression, anaemia and neuropathy. Due to their close interactions with people and livestock, dogs can serve as reservoirs and transmit these pathogens to humans and other animals. The data from this research can be valuable for managing and controlling related diseases and complications in Iran and possibly neighbouring countries. Pertinent data for this study was gathered without time limitations until 1 March 2022, from different databases. Of all the inspected studies, 26 were eligible based on the inclusion criteria. The Egger test result and asymmetry in the funnel plot revealed significant publication bias; therefore, the meta‐analysis model was corrected with the trim‐and‐fill method. After correction, the prevalence of rickettsial infections among dogs varies by genus – 20.1% for Anaplasma spp. and 10% for Ehrlichia spp. – with an overall prevalence estimated at 18.3% by random‐effects analysis. The highest and lowest estimated pooled prevalences were associated with the southwestern (38.5%) and southern (0.3%) provinces of Iran, respectively. The pooled prevalence of rickettsial infection was higher in female dogs (OR = 1.198; p < 0.978; 95% CI, 0.842–1.705) and in dogs ≤2 years (OR = 1.014; p < 0.312; 95% CI, 0.598–1.72), but the difference was not statistically significant. Ultimately, the pooled prevalence of rickettsial infections among dogs is relatively low compared to other countries like Qatar, Iraq, Saudi Arabia and Turkey, which are nearby Iran. Given the significant clinical outcomes of this disease, necessary measures for prevention should be taken.https://doi.org/10.1002/vms3.1381AnaplasmaEhrlichiaIranmeta‐analysisRickettsia |
| spellingShingle | Arman Abdous Mehdi Rahnama Farzane Shams Mohammad Jokar Vahid Rahmanian Mehran Farhoodi Aryan Abbassioun Mohammad Sadegh Kamjoo Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study Veterinary Medicine and Science Anaplasma Ehrlichia Iran meta‐analysis Rickettsia |
| title | Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study |
| title_full | Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study |
| title_fullStr | Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study |
| title_full_unstemmed | Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study |
| title_short | Prevalence of Anaplasma, Ehrlichia and Rickettsia infections in dogs in Iran: A meta‐analysis study |
| title_sort | prevalence of anaplasma ehrlichia and rickettsia infections in dogs in iran a meta analysis study |
| topic | Anaplasma Ehrlichia Iran meta‐analysis Rickettsia |
| url | https://doi.org/10.1002/vms3.1381 |
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