The defective gut colonization of Candida albicans hog1 MAPK mutants is restored by overexpressing the transcriptional regulator of the white opaque transition WOR1

The defective gut colonization of Candida albicans hog1 MAPK mutants is restored by overexpressing the transcriptional regulator of the white opaque transition WOR1

ABSTRACTThe transcriptional master regulator of the white opaque transition of Candida albicans WOR1 is important for the adaptation to the commensal lifestyle in the mammalian gut, a major source of invasive candidiasis. We have generated cells that overproduce Wor1 in mutants defective in the Hog1...

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Bibliographic Details
Main Authors: Elvira Román, Daniel Prieto, Susana Hidalgo-Vico, Rebeca Alonso-Monge, Jesús Pla
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Candida albicans
gut colonization
commensalism
Wor1
Hog1
MAPK
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2174294

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