Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)

Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes....

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Bibliographic Details
Main Authors: Hamid Reza Hatamian, Babak Bakhshayesh, Nazanin Rahman-A
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2014-04-01
Series:International Clinical Neuroscience Journal
Online Access:http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4
Description
Summary:Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. These lesions mimic infarction. Here, we reported a case of MELAS with rare neuroimaging finding of hemispheric cortical thickening on T2/FLAIR images with intracortical nodular gadolinium enhancement; then we discussed the clinical and radiological differential diagnoses of it.
ISSN:2383-1871
2383-2096