Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2014-04-01
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| Series: | International Clinical Neuroscience Journal |
| Online Access: | http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4 |
| _version_ | 1818558780355379200 |
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| author | Hamid Reza Hatamian Babak Bakhshayesh Nazanin Rahman-A |
| author_facet | Hamid Reza Hatamian Babak Bakhshayesh Nazanin Rahman-A |
| author_sort | Hamid Reza Hatamian |
| collection | DOAJ |
| description | Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. These lesions mimic infarction. Here, we reported a case of MELAS with rare neuroimaging finding of hemispheric cortical thickening on T2/FLAIR images with intracortical nodular gadolinium enhancement; then we discussed the clinical and radiological differential diagnoses of it. |
| first_indexed | 2024-12-14T00:16:44Z |
| format | Article |
| id | doaj.art-14bd65874689477daead9f55059c0cd5 |
| institution | Directory Open Access Journal |
| issn | 2383-1871 2383-2096 |
| language | English |
| last_indexed | 2024-12-14T00:16:44Z |
| publishDate | 2014-04-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | International Clinical Neuroscience Journal |
| spelling | doaj.art-14bd65874689477daead9f55059c0cd52022-12-21T23:25:27ZengShahid Beheshti University of Medical SciencesInternational Clinical Neuroscience Journal2383-18712383-20962014-04-0112697210.22037/icnj.v1i2.6754icnj-3044Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)Hamid Reza Hatamian0Babak Bakhshayesh1Nazanin Rahman-A2Department of Neurology, Guilan University of Medical Sciences, Guilan, IranDepartment of Neurology, Guilan University of Medical Sciences, Guilan, IranDepartment of Neurology, Guilan University of Medical Sciences, Guilan, IranPatients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. These lesions mimic infarction. Here, we reported a case of MELAS with rare neuroimaging finding of hemispheric cortical thickening on T2/FLAIR images with intracortical nodular gadolinium enhancement; then we discussed the clinical and radiological differential diagnoses of it.http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4 |
| spellingShingle | Hamid Reza Hatamian Babak Bakhshayesh Nazanin Rahman-A Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) International Clinical Neuroscience Journal |
| title | Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) |
| title_full | Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) |
| title_fullStr | Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) |
| title_full_unstemmed | Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) |
| title_short | Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS) |
| title_sort | unilateral cortical thickening and hyper intensity due to mitochondrial encephalopathy lactic acidosis and stroke like episodes melas |
| url | http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4 |
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