Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt

<p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The ai...

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Main Authors: Abd ElHafeez Samar, Sallam Sunny A, Gad Zahira M, Zoccali Carmine, Torino Claudia, Tripepi Giovanni, ElWakil Hala S, Awad Noha M
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Nephrology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2369/13/170
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author Abd ElHafeez Samar
Sallam Sunny A
Gad Zahira M
Zoccali Carmine
Torino Claudia
Tripepi Giovanni
ElWakil Hala S
Awad Noha M
author_facet Abd ElHafeez Samar
Sallam Sunny A
Gad Zahira M
Zoccali Carmine
Torino Claudia
Tripepi Giovanni
ElWakil Hala S
Awad Noha M
author_sort Abd ElHafeez Samar
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SF<sup>TM</sup>) version 1.3 questionnaire in a representative series of Egyptian CKD patients.</p> <p>Methods</p> <p>KDQOL-SF<sup>TM</sup> version 1.3 was translated into Arabic by two independent translators, and then subsequently translated back into English. After translation disparities were reconciled, the final Arabic questionnaire was tested by interviewing 100 pre-dialysis CKD (stage 1-4) patients randomly selected from outpatients attending the Nephrology clinic at the Main Alexandria University Hospital. Test re-test reliability was performed, with a subsample of 50 consecutive CKD patients, by two interviews 7 days apart and internal consistency estimated by Cronbach’s α. Discriminant, concept, and construct validity were assessed.</p> <p>Results</p> <p>All items of SF-36 met the criterion for internal consistency and were reproducible. Of the 10 kidney disease targeted scales, only three had Cronbach’s α <0.7: quality of social interaction (0.23), work status (0.28), and cognitive function (0.60). All disease specific scales were reproducible. Results from discriminant validity showed that the study questionnaire could discriminate between patients’ subgroups. As for concept validity, the correlation between all domains of the questionnaire with overall health ratewas significant for all domains except for the work status, sexual function, emotional wellbeing, and role emotional. Furthermore, the correlation between the disease specific domains and the two composite summaries of SF-36 (physical and mental composite summaries) was significant for all domains except for sexual function with mental composite summary. Construct validity was indicated by the observation that the majority of the domains of the kidney disease targeted scale of KDQOL-SF<sup>TM</sup> 1.3 were significantly inter-correlated. Finally, principal component analysis of the kidney disease targeted scale indicated that this part of the questionnaire could be summarized into 10 factors that together explained 70.9% of the variance.</p> <p>Conclusion</p> <p>The results suggest that this Arabic version of the KDQOL-SF<sup>TM</sup> 1.3 questionnaire is a valid and reliable tool for use in Egyptian patients with CKD.</p>
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spelling doaj.art-14bea3c2457045c182d408525de98da82022-12-22T03:07:44ZengBMCBMC Nephrology1471-23692012-12-0113117010.1186/1471-2369-13-170Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in EgyptAbd ElHafeez SamarSallam Sunny AGad Zahira MZoccali CarmineTorino ClaudiaTripepi GiovanniElWakil Hala SAwad Noha M<p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SF<sup>TM</sup>) version 1.3 questionnaire in a representative series of Egyptian CKD patients.</p> <p>Methods</p> <p>KDQOL-SF<sup>TM</sup> version 1.3 was translated into Arabic by two independent translators, and then subsequently translated back into English. After translation disparities were reconciled, the final Arabic questionnaire was tested by interviewing 100 pre-dialysis CKD (stage 1-4) patients randomly selected from outpatients attending the Nephrology clinic at the Main Alexandria University Hospital. Test re-test reliability was performed, with a subsample of 50 consecutive CKD patients, by two interviews 7 days apart and internal consistency estimated by Cronbach’s α. Discriminant, concept, and construct validity were assessed.</p> <p>Results</p> <p>All items of SF-36 met the criterion for internal consistency and were reproducible. Of the 10 kidney disease targeted scales, only three had Cronbach’s α <0.7: quality of social interaction (0.23), work status (0.28), and cognitive function (0.60). All disease specific scales were reproducible. Results from discriminant validity showed that the study questionnaire could discriminate between patients’ subgroups. As for concept validity, the correlation between all domains of the questionnaire with overall health ratewas significant for all domains except for the work status, sexual function, emotional wellbeing, and role emotional. Furthermore, the correlation between the disease specific domains and the two composite summaries of SF-36 (physical and mental composite summaries) was significant for all domains except for sexual function with mental composite summary. Construct validity was indicated by the observation that the majority of the domains of the kidney disease targeted scale of KDQOL-SF<sup>TM</sup> 1.3 were significantly inter-correlated. Finally, principal component analysis of the kidney disease targeted scale indicated that this part of the questionnaire could be summarized into 10 factors that together explained 70.9% of the variance.</p> <p>Conclusion</p> <p>The results suggest that this Arabic version of the KDQOL-SF<sup>TM</sup> 1.3 questionnaire is a valid and reliable tool for use in Egyptian patients with CKD.</p>http://www.biomedcentral.com/1471-2369/13/170Chronic kidney diseaseEgyptHealth-related quality of lifeKDQOL-SF<sup>TM</sup> 1.3Questionnaire validation
spellingShingle Abd ElHafeez Samar
Sallam Sunny A
Gad Zahira M
Zoccali Carmine
Torino Claudia
Tripepi Giovanni
ElWakil Hala S
Awad Noha M
Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
BMC Nephrology
Chronic kidney disease
Egypt
Health-related quality of life
KDQOL-SF<sup>TM</sup> 1.3
Questionnaire validation
title Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
title_full Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
title_fullStr Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
title_full_unstemmed Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
title_short Cultural adaptation and validation of the “Kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3” questionnaire in Egypt
title_sort cultural adaptation and validation of the kidney disease and quality of life short form kdqol sf™ version 1 3 questionnaire in egypt
topic Chronic kidney disease
Egypt
Health-related quality of life
KDQOL-SF<sup>TM</sup> 1.3
Questionnaire validation
url http://www.biomedcentral.com/1471-2369/13/170
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