Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats

Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats

BackgroundInflammation remains a crucial factor for progression of cardiac diseases and cardiac hypertrophy remains an important cause of cardiac failure over all age groups. As a key regulator of inflammation, toll-like receptor 4 (TLR4) plays an important role in pathogenesis of cardiac diseases....

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Bibliographic Details
Main Authors: Parmeshwar B. Katare, Pankaj K. Bagul, Amit K. Dinda, Sanjay K. Banerjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
cardiac hypertrophy
isoproterenol
toll-like receptor 4
lipopolysaccharide
RS-LPS
oxidative phosphorylation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00719/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00719/full

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