The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction?
Background. This study aimed to investigate the association of preoperative right heart filling indicators with outcomes after coronary artery bypass grafting (CABG) at an 18 month follow up. Methods. Patients who underwent CABG at a single center were included in this study. In addition to the base...
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MDPI AG
2023-01-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/10/1/18 |
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| author | Alexey N. Sumin Anna V. Shcheglova Ekaterina V. Korok Tatjana Ju. Sergeeva |
| author_facet | Alexey N. Sumin Anna V. Shcheglova Ekaterina V. Korok Tatjana Ju. Sergeeva |
| author_sort | Alexey N. Sumin |
| collection | DOAJ |
| description | Background. This study aimed to investigate the association of preoperative right heart filling indicators with outcomes after coronary artery bypass grafting (CABG) at an 18 month follow up. Methods. Patients who underwent CABG at a single center were included in this study. In addition to the baseline preoperative indicators and perioperative data, initial parameters of the right ventricle (RV) systolic and diastolic function were assessed. Results. Among the 189 patients, a total of 19 (10.0%) MACE (cardiovascular death, nonfatal myocardial infarction and stroke) were recorded during an 18 month follow up. In patients with the development of MACE during the initial examination, the following changes in RV function were revealed compared with the group without MACE: a decrease in the e’t index (8.2 versus 9.6 cm/s, <i>p</i> = 0.029), an increase in the Et/e’t ratio (5.25 vs. 4.42, <i>p</i> = 0.049) and more frequent presence of RV pseudonormal filling (<i>p</i> = 0.03). In the binary logistic regression analysis, the development of MACE 18 months after CABG was associated with the nonconduction of PCI before surgery, the presence of peripheral atherosclerosis, an increase in IVST and Et/e’t and a decrease in LVEF. Conclusions. RV diastolic dysfunction in the preoperative period was associated with the development of MACE within 18 months after CABG, and the ratio Et/e’t was one of the independent predictors of MACE in a multiple regression analysis. This makes it expedient to include an assessment of not only systolic but also diastolic RV function in the preoperative examination. The inclusion of an assessment of RV diastolic function in the pre-CABG evaluation of patients deserves further study. |
| first_indexed | 2024-03-09T12:13:32Z |
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| language | English |
| last_indexed | 2024-03-09T12:13:32Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
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| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-14c654528d6e4e81832699d37698dd3b2023-11-30T22:49:12ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252023-01-011011810.3390/jcdd10010018The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction?Alexey N. Sumin0Anna V. Shcheglova1Ekaterina V. Korok2Tatjana Ju. Sergeeva3Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Disease”, Sosnoviy Blvd., 6, 650002 Kemerovo, RussiaFederal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Disease”, Sosnoviy Blvd., 6, 650002 Kemerovo, RussiaFederal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Disease”, Sosnoviy Blvd., 6, 650002 Kemerovo, RussiaFederal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Disease”, Sosnoviy Blvd., 6, 650002 Kemerovo, RussiaBackground. This study aimed to investigate the association of preoperative right heart filling indicators with outcomes after coronary artery bypass grafting (CABG) at an 18 month follow up. Methods. Patients who underwent CABG at a single center were included in this study. In addition to the baseline preoperative indicators and perioperative data, initial parameters of the right ventricle (RV) systolic and diastolic function were assessed. Results. Among the 189 patients, a total of 19 (10.0%) MACE (cardiovascular death, nonfatal myocardial infarction and stroke) were recorded during an 18 month follow up. In patients with the development of MACE during the initial examination, the following changes in RV function were revealed compared with the group without MACE: a decrease in the e’t index (8.2 versus 9.6 cm/s, <i>p</i> = 0.029), an increase in the Et/e’t ratio (5.25 vs. 4.42, <i>p</i> = 0.049) and more frequent presence of RV pseudonormal filling (<i>p</i> = 0.03). In the binary logistic regression analysis, the development of MACE 18 months after CABG was associated with the nonconduction of PCI before surgery, the presence of peripheral atherosclerosis, an increase in IVST and Et/e’t and a decrease in LVEF. Conclusions. RV diastolic dysfunction in the preoperative period was associated with the development of MACE within 18 months after CABG, and the ratio Et/e’t was one of the independent predictors of MACE in a multiple regression analysis. This makes it expedient to include an assessment of not only systolic but also diastolic RV function in the preoperative examination. The inclusion of an assessment of RV diastolic function in the pre-CABG evaluation of patients deserves further study.https://www.mdpi.com/2308-3425/10/1/18coronary artery bypass surgeryright ventriclediastolic functionpostoperative outcomes |
| spellingShingle | Alexey N. Sumin Anna V. Shcheglova Ekaterina V. Korok Tatjana Ju. Sergeeva The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? Journal of Cardiovascular Development and Disease coronary artery bypass surgery right ventricle diastolic function postoperative outcomes |
| title | The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? |
| title_full | The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? |
| title_fullStr | The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? |
| title_full_unstemmed | The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? |
| title_short | The Outcomes of Coronary Artery Bypass Surgery after 18 Months—Is There an Influence of the Initial Right Ventricle Diastolic Dysfunction? |
| title_sort | outcomes of coronary artery bypass surgery after 18 months is there an influence of the initial right ventricle diastolic dysfunction |
| topic | coronary artery bypass surgery right ventricle diastolic function postoperative outcomes |
| url | https://www.mdpi.com/2308-3425/10/1/18 |
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