ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS
The aim of the study. Study of electrophysiological signs ofmyocardial metabolic disorders (MMD) and the search for their associations with metabolic syndrome (MS) in men with coronary atherosclerosis (CA). Materials and methods. The study included 123 men with stenotic CA, verified during coronary...
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| Format: | Article |
| Language: | Russian |
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Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics
2016-03-01
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| Series: | Атеросклероз |
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| Online Access: | https://ateroskleroz.elpub.ru/jour/article/view/5/5 |
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| author | N. A. Timoshenko Yu. I. Ragino O. V. Pushkina A. M. Chernyavskii S. Yu. Tcimbal M. I. Voevoda |
| author_facet | N. A. Timoshenko Yu. I. Ragino O. V. Pushkina A. M. Chernyavskii S. Yu. Tcimbal M. I. Voevoda |
| author_sort | N. A. Timoshenko |
| collection | DOAJ |
| description | The aim of the study. Study of electrophysiological signs ofmyocardial metabolic disorders (MMD) and the search for their associations with metabolic syndrome (MS) in men with coronary atherosclerosis (CA). Materials and methods. The study included 123 men with stenotic CA, verified during coronary angiography (CAG), without acute coronary syndrome (ACS) and with stable angina functional class (FC) II-IV.Was spend ECG alone in 12 standard leads. We analyzed ECG signs of MMD (length of the interval QT, above the contour >5mm, ST segment depression below the contour >5mm non-ischemic type, T-wave changes, syndrome TV1> TV6, signs of left ventricular hypertrophy (LVH), arrhythmias and asequence). Evaluated components and markers MS: waist circumference (WC), body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP) blood levels of total cholesterol (TC), cholesterol of lowand high-density lipoproteins (LDL-cholesterol, HDL-cholesterol), c-peptide, and glucose, tumor necrosis factor (TNF-alpha), interleukin 6 (IL-6). Results and discussion. It was found that men with a significant stenotic atherosclerosis of one or more branches of the coronary arteries has a high incidence of MS (69%), its features / components and nonspecific ECG signs of MMD. In addition, men with SC and MS or with the frequency component of the electrophysiological signs MMD ECG signs of LVHand syndrome TV1> TV6 higher by more than 1.5 times in comparison with the absence of MS. Conclusion. Results of the study reflect the impact of common metabolic disorders in the body of the emergence and development of not only the metabolic syndrome, and metabolic myocardial damage. |
| first_indexed | 2024-04-11T01:43:00Z |
| format | Article |
| id | doaj.art-14cdf57786194a4096e7492e63e88caf |
| institution | Directory Open Access Journal |
| issn | 2078-256X |
| language | Russian |
| last_indexed | 2024-04-11T01:43:00Z |
| publishDate | 2016-03-01 |
| publisher | Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics |
| record_format | Article |
| series | Атеросклероз |
| spelling | doaj.art-14cdf57786194a4096e7492e63e88caf2023-01-03T08:10:01ZrusSiberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and GeneticsАтеросклероз2078-256X2016-03-011211927ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSISN. A. Timoshenko0Yu. I. Ragino1 O. V. Pushkina2A. M. Chernyavskii3S. Yu. Tcimbal4M. I. Voevoda5Institute of Internal and Preventive Medicine SB RAMS Russian FederationInstitute of Internal and Preventive Medicine SB RAMS Russian FederationInstitute of Internal and Preventive Medicine SB RAMS Russian FederationResearch State of Circulation Pathology, Ministry of Public Health and Social Development Russian FederationResearch State of Circulation Pathology, Ministry of Public Health and Social Development Russian FederationInstitute of Internal and Preventive Medicine SB RAMS Russian FederationThe aim of the study. Study of electrophysiological signs ofmyocardial metabolic disorders (MMD) and the search for their associations with metabolic syndrome (MS) in men with coronary atherosclerosis (CA). Materials and methods. The study included 123 men with stenotic CA, verified during coronary angiography (CAG), without acute coronary syndrome (ACS) and with stable angina functional class (FC) II-IV.Was spend ECG alone in 12 standard leads. We analyzed ECG signs of MMD (length of the interval QT, above the contour >5mm, ST segment depression below the contour >5mm non-ischemic type, T-wave changes, syndrome TV1> TV6, signs of left ventricular hypertrophy (LVH), arrhythmias and asequence). Evaluated components and markers MS: waist circumference (WC), body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP) blood levels of total cholesterol (TC), cholesterol of lowand high-density lipoproteins (LDL-cholesterol, HDL-cholesterol), c-peptide, and glucose, tumor necrosis factor (TNF-alpha), interleukin 6 (IL-6). Results and discussion. It was found that men with a significant stenotic atherosclerosis of one or more branches of the coronary arteries has a high incidence of MS (69%), its features / components and nonspecific ECG signs of MMD. In addition, men with SC and MS or with the frequency component of the electrophysiological signs MMD ECG signs of LVHand syndrome TV1> TV6 higher by more than 1.5 times in comparison with the absence of MS. Conclusion. Results of the study reflect the impact of common metabolic disorders in the body of the emergence and development of not only the metabolic syndrome, and metabolic myocardial damage.https://ateroskleroz.elpub.ru/jour/article/view/5/5electrophysiological signsmyocardial metabolic disorderscoronary atherosclerosismetabolic syndrome |
| spellingShingle | N. A. Timoshenko Yu. I. Ragino O. V. Pushkina A. M. Chernyavskii S. Yu. Tcimbal M. I. Voevoda ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS Атеросклероз electrophysiological signs myocardial metabolic disorders coronary atherosclerosis metabolic syndrome |
| title | ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS |
| title_full | ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS |
| title_fullStr | ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS |
| title_full_unstemmed | ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS |
| title_short | ELECTROPHYSIOLOGICAL SIGNS OF MYOCARDIAL DAMAGE ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS IN MEN WITH CORONARY ATHEROSCLEROSIS |
| title_sort | electrophysiological signs of myocardial damage associated with the metabolic syndrome and its components in men with coronary atherosclerosis |
| topic | electrophysiological signs myocardial metabolic disorders coronary atherosclerosis metabolic syndrome |
| url | https://ateroskleroz.elpub.ru/jour/article/view/5/5 |
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