Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity

Kinetics of the synthesis of 3-[3-quinoxaline(1H)-one]propionic acid (I) were performed. This compound was achieved from reaction between o-phenylenediamine and α-ketoglutaric acid under different experimental conditions, and it was sent to the National Cancer Institute (USA) for its pharmacologi...

Full description

Bibliographic Details
Main Authors: Gabriela A. Rodrigo, Diana G. Bekerman, Adriana E. Robinsohn, Beatriz M. Fernández
Format: Article
Language:English
Published: MDPI AG 2000-03-01
Series:Molecules
Subjects:
n/a
Online Access:http://www.mdpi.com/1420-3049/5/3/358/
_version_ 1811253110289465344
author Gabriela A. Rodrigo
Diana G. Bekerman
Adriana E. Robinsohn
Beatriz M. Fernández
author_facet Gabriela A. Rodrigo
Diana G. Bekerman
Adriana E. Robinsohn
Beatriz M. Fernández
author_sort Gabriela A. Rodrigo
collection DOAJ
description Kinetics of the synthesis of 3-[3-quinoxaline(1H)-one]propionic acid (I) were performed. This compound was achieved from reaction between o-phenylenediamine and α-ketoglutaric acid under different experimental conditions, and it was sent to the National Cancer Institute (USA) for its pharmacological evaluation.
first_indexed 2024-04-12T16:45:49Z
format Article
id doaj.art-14cf976b920c4039ac4bd42ffb369fda
institution Directory Open Access Journal
issn 1420-3049
language English
last_indexed 2024-04-12T16:45:49Z
publishDate 2000-03-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj.art-14cf976b920c4039ac4bd42ffb369fda2022-12-22T03:24:34ZengMDPI AGMolecules1420-30492000-03-015335835910.3390/50300358Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV ActivityGabriela A. RodrigoDiana G. BekermanAdriana E. RobinsohnBeatriz M. FernándezKinetics of the synthesis of 3-[3-quinoxaline(1H)-one]propionic acid (I) were performed. This compound was achieved from reaction between o-phenylenediamine and α-ketoglutaric acid under different experimental conditions, and it was sent to the National Cancer Institute (USA) for its pharmacological evaluation.http://www.mdpi.com/1420-3049/5/3/358/n/a
spellingShingle Gabriela A. Rodrigo
Diana G. Bekerman
Adriana E. Robinsohn
Beatriz M. Fernández
Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
Molecules
n/a
title Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
title_full Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
title_fullStr Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
title_full_unstemmed Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
title_short Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity
title_sort synthesis and physicochemical study of a quinoxaline derivative with potencial antineoplasic or anti hiv activity
topic n/a
url http://www.mdpi.com/1420-3049/5/3/358/
work_keys_str_mv AT gabrielaarodrigo synthesisandphysicochemicalstudyofaquinoxalinederivativewithpotencialantineoplasicorantihivactivity
AT dianagbekerman synthesisandphysicochemicalstudyofaquinoxalinederivativewithpotencialantineoplasicorantihivactivity
AT adrianaerobinsohn synthesisandphysicochemicalstudyofaquinoxalinederivativewithpotencialantineoplasicorantihivactivity
AT beatrizmfernaƒandez synthesisandphysicochemicalstudyofaquinoxalinederivativewithpotencialantineoplasicorantihivactivity