Immunological study of COVID-19 vaccine candidate based on recombinant spike trimer protein from different SARS-CoV-2 variants of concern

Immunological study of COVID-19 vaccine candidate based on recombinant spike trimer protein from different SARS-CoV-2 variants of concern

The emergency of new SARS-CoV-2 variants that feature increased immune escape marks an urgent demand for better vaccines that will provide broader immunogenicity. Here, we evaluated the immunogenic capacity of vaccine candidates based on the recombinant trimeric spike protein (S) of different SARS-C...

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Bibliographic Details
Main Authors: Erika Rudi, Pablo Martin Aispuro, Eugenia Zurita, Maria M. Gonzalez Lopez Ledesma, Daniela Bottero, Juan Malito, Magali Gabrielli, Emilia Gaillard, Matthew Stuible, Yves Durocher, Andrea V. Gamarnik, Andrés Wigdorovitz, Daniela Hozbor
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
mice immunization
spike trimeric protein
immunogenicity
vaccine candidate
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020159/full

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