Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects

Abstract This report presents the case of a patient with gestational trophoblastic neoplasia after a partial hydatidiform mole formed in the Fallopian tube. Ectopic molar pregnancy is a rare condition, with an estimated incidence of 1 in every 20,000 to 100,000 pregnancies; less than 300 cases of it...

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Main Authors: Consuelo Lozoya López, Vania Gloria Silami Lopes, Fabiana Rodrigues Resende, Jessica Lara Steim, Lilian Padrón, Sue Yazaki Sun, Edward Araujo Júnior, Antonio Braga
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2018-05-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000500294&tlng=en
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author Consuelo Lozoya López
Vania Gloria Silami Lopes
Fabiana Rodrigues Resende
Jessica Lara Steim
Lilian Padrón
Sue Yazaki Sun
Edward Araujo Júnior
Antonio Braga
author_facet Consuelo Lozoya López
Vania Gloria Silami Lopes
Fabiana Rodrigues Resende
Jessica Lara Steim
Lilian Padrón
Sue Yazaki Sun
Edward Araujo Júnior
Antonio Braga
author_sort Consuelo Lozoya López
collection DOAJ
description Abstract This report presents the case of a patient with gestational trophoblastic neoplasia after a partial hydatidiform mole formed in the Fallopian tube. Ectopic molar pregnancy is a rare condition, with an estimated incidence of 1 in every 20,000 to 100,000 pregnancies; less than 300 cases of it have been reported in the Western literature. The present report is important because it presents current diagnostic criteria for this rare condition, which has been incorrectly diagnosed in the past, not only morphologically but also immunohistochemically. It also draws the attention of obstetricians to the occurrence of ectopic molar pregnancy, which tends to progress to Fallopian tube rupture more often than in cases of ectopic non-molar pregnancy. Progression to gestational trophoblastic neoplasia ensures that patients with ectopic molar pregnancy must undergo postmolar monitoring, which must be just as thorough as that of patients with intrauterine hydatidiform moles, even if chemotherapy results in high cure rates.
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spelling doaj.art-14d33179aaf1435bab053ab6304e75fd2022-12-21T19:22:41ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032018-05-0140529429910.1055/s-0038-1653976Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic AspectsConsuelo Lozoya LópezVania Gloria Silami LopesFabiana Rodrigues ResendeJessica Lara SteimLilian PadrónSue Yazaki SunEdward Araujo JúniorAntonio BragaAbstract This report presents the case of a patient with gestational trophoblastic neoplasia after a partial hydatidiform mole formed in the Fallopian tube. Ectopic molar pregnancy is a rare condition, with an estimated incidence of 1 in every 20,000 to 100,000 pregnancies; less than 300 cases of it have been reported in the Western literature. The present report is important because it presents current diagnostic criteria for this rare condition, which has been incorrectly diagnosed in the past, not only morphologically but also immunohistochemically. It also draws the attention of obstetricians to the occurrence of ectopic molar pregnancy, which tends to progress to Fallopian tube rupture more often than in cases of ectopic non-molar pregnancy. Progression to gestational trophoblastic neoplasia ensures that patients with ectopic molar pregnancy must undergo postmolar monitoring, which must be just as thorough as that of patients with intrauterine hydatidiform moles, even if chemotherapy results in high cure rates.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000500294&tlng=enectopic pregnancyhydatidiform molegestational trophoblastic neoplasiapathology
spellingShingle Consuelo Lozoya López
Vania Gloria Silami Lopes
Fabiana Rodrigues Resende
Jessica Lara Steim
Lilian Padrón
Sue Yazaki Sun
Edward Araujo Júnior
Antonio Braga
Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
Revista Brasileira de Ginecologia e Obstetrícia
ectopic pregnancy
hydatidiform mole
gestational trophoblastic neoplasia
pathology
title Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
title_full Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
title_fullStr Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
title_full_unstemmed Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
title_short Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects
title_sort gestational trophoblastic neoplasia after ectopic molar pregnancy clinical diagnostic and therapeutic aspects
topic ectopic pregnancy
hydatidiform mole
gestational trophoblastic neoplasia
pathology
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018000500294&tlng=en
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