Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)

Abstract X-linked hypophosphatemia (XLH) is a rare disease of elevated fibroblast growth factor 23 (FGF23) production that leads to hypophosphatemia and impaired mineralization of bone and teeth. The clinical manifestations of XLH include a high prevalence of dental abscesses and periodontal disease...

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Bibliographic Details
Main Authors: Kelsey A. Carpenter, Delia O. Alkhatib, Bryan A. Dulion, Elizabeth Guirado, Shreya Patel, Yinghua Chen, Anne George, Ryan D. Ross
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-023-00252-1