A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Althoug...
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MDPI AG
2018-03-01
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Online Access: | http://www.mdpi.com/1660-3397/16/4/106 |
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author | Fangping Li Ping Luo Huazhong Liu |
author_facet | Fangping Li Ping Luo Huazhong Liu |
author_sort | Fangping Li |
collection | DOAJ |
description | Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Although SIP has been proved to be multifaceted, most of the reported evidence has illuminated its chemopreventive and antineoplastic activities. As a natural product playing a role in cancer treatment, SIP may be used as chemotherapeutic ancillary agent or functional food. Based on the current findings on SIP, we have summarized four topics in this review, including: chemopreventive, antineoplastic, chemosensitive, and procoagulant and anticoagulant activities, which are correlative closely with the actions of anticancer agents on cancer patients, such as anticancer, toxicity and thrombogenesis, with the latter two actions being common causes of death in cancer cases exposed to chemotherapeutic agents. |
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issn | 1660-3397 |
language | English |
last_indexed | 2024-04-11T21:53:43Z |
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spelling | doaj.art-14d55c2da088406ba3ecc75687c87cc42022-12-22T04:01:10ZengMDPI AGMarine Drugs1660-33972018-03-0116410610.3390/md16040106md16040106A Potential Adjuvant Agent of Chemotherapy: Sepia Ink PolysaccharidesFangping Li0Ping Luo1Huazhong Liu2College of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaCollege of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaCollege of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaSepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Although SIP has been proved to be multifaceted, most of the reported evidence has illuminated its chemopreventive and antineoplastic activities. As a natural product playing a role in cancer treatment, SIP may be used as chemotherapeutic ancillary agent or functional food. Based on the current findings on SIP, we have summarized four topics in this review, including: chemopreventive, antineoplastic, chemosensitive, and procoagulant and anticoagulant activities, which are correlative closely with the actions of anticancer agents on cancer patients, such as anticancer, toxicity and thrombogenesis, with the latter two actions being common causes of death in cancer cases exposed to chemotherapeutic agents.http://www.mdpi.com/1660-3397/16/4/106Sepia ink polysaccharideschemopreventionantitumourchemosensitizationanticoagulation |
spellingShingle | Fangping Li Ping Luo Huazhong Liu A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides Marine Drugs Sepia ink polysaccharides chemoprevention antitumour chemosensitization anticoagulation |
title | A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides |
title_full | A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides |
title_fullStr | A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides |
title_full_unstemmed | A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides |
title_short | A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides |
title_sort | potential adjuvant agent of chemotherapy sepia ink polysaccharides |
topic | Sepia ink polysaccharides chemoprevention antitumour chemosensitization anticoagulation |
url | http://www.mdpi.com/1660-3397/16/4/106 |
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