A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides

Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Althoug...

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Main Authors: Fangping Li, Ping Luo, Huazhong Liu
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/4/106
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author Fangping Li
Ping Luo
Huazhong Liu
author_facet Fangping Li
Ping Luo
Huazhong Liu
author_sort Fangping Li
collection DOAJ
description Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Although SIP has been proved to be multifaceted, most of the reported evidence has illuminated its chemopreventive and antineoplastic activities. As a natural product playing a role in cancer treatment, SIP may be used as chemotherapeutic ancillary agent or functional food. Based on the current findings on SIP, we have summarized four topics in this review, including: chemopreventive, antineoplastic, chemosensitive, and procoagulant and anticoagulant activities, which are correlative closely with the actions of anticancer agents on cancer patients, such as anticancer, toxicity and thrombogenesis, with the latter two actions being common causes of death in cancer cases exposed to chemotherapeutic agents.
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spelling doaj.art-14d55c2da088406ba3ecc75687c87cc42022-12-22T04:01:10ZengMDPI AGMarine Drugs1660-33972018-03-0116410610.3390/md16040106md16040106A Potential Adjuvant Agent of Chemotherapy: Sepia Ink PolysaccharidesFangping Li0Ping Luo1Huazhong Liu2College of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaCollege of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaCollege of Chemistry & Environment, Guangdong Ocean University, Zhanjiang 524088, ChinaSepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartrami), cuttlefish Sepiella maindroni, and cuttlefish Sepia esculenta ink. Although SIP has been proved to be multifaceted, most of the reported evidence has illuminated its chemopreventive and antineoplastic activities. As a natural product playing a role in cancer treatment, SIP may be used as chemotherapeutic ancillary agent or functional food. Based on the current findings on SIP, we have summarized four topics in this review, including: chemopreventive, antineoplastic, chemosensitive, and procoagulant and anticoagulant activities, which are correlative closely with the actions of anticancer agents on cancer patients, such as anticancer, toxicity and thrombogenesis, with the latter two actions being common causes of death in cancer cases exposed to chemotherapeutic agents.http://www.mdpi.com/1660-3397/16/4/106Sepia ink polysaccharideschemopreventionantitumourchemosensitizationanticoagulation
spellingShingle Fangping Li
Ping Luo
Huazhong Liu
A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
Marine Drugs
Sepia ink polysaccharides
chemoprevention
antitumour
chemosensitization
anticoagulation
title A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
title_full A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
title_fullStr A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
title_full_unstemmed A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
title_short A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
title_sort potential adjuvant agent of chemotherapy sepia ink polysaccharides
topic Sepia ink polysaccharides
chemoprevention
antitumour
chemosensitization
anticoagulation
url http://www.mdpi.com/1660-3397/16/4/106
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