RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients

RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients

Abstract Introduction Mesenchymal stem cells (MSCs) have the ability to differentiate into different types of cells of the mesenchymal lineage, such as osteocytes, chondrocytes, and adipocytes. It is also known that under inflammatory stimuli or in the appropriate experimental conditions, they can a...

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Bibliographic Details
Main Authors: Jose Ramon Lamas, Benjamin Fernandez-Gutierrez, Arkaitz Mucientes, Fernando Marco, Yaiza Lopiz, Juan Angel Jover, Lydia Abasolo, Luis Rodríguez-Rodríguez
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Arthritis Research & Therapy
Subjects:
Mesenchymal stem cells
Rheumatoid arthritis
RNA-seq
Immunomodulation
Online Access:http://link.springer.com/article/10.1186/s13075-019-1894-y

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