DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets.

DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets.

Proteins that are known only at a sequence level outnumber those with an experimental characterization by orders of magnitude. Classifying protein regions (domains) into homologous families can generate testable functional hypotheses for yet unannotated sequences. Existing domain family resources ty...

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Bibliographic Details
Main Authors:	Elena Tea Russo, Federico Barone, Alex Bateman, Stefano Cozzini, Marco Punta, Alessandro Laio
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-10-01
Series:	PLoS Computational Biology
Online Access:	https://doi.org/10.1371/journal.pcbi.1010610

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