Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference?
Introduction: In stroke the inflammatory response depends on the neutrophils and leukocytes, reason why the neutrophil/lymphocyte (N/L) and mean platelet volume/platelet count (MPV/PC) indexes are considered to assess stroke. Aim: We aim to determine which index, N/L index or mean platelet volume/pl...
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| Format: | Article |
| Language: | English |
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Publicaciones Permanyer
2022-04-01
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| Series: | The Journal of Latin American Geriatric Medicine |
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| Online Access: | https://www.jgeriatricmedicine.com/frame_esp.php?id=74 |
| _version_ | 1797976566596108288 |
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| author | Juan J. Gómez-Piña Amairani Sierra-Hernández |
| author_facet | Juan J. Gómez-Piña Amairani Sierra-Hernández |
| author_sort | Juan J. Gómez-Piña |
| collection | DOAJ |
| description | Introduction: In stroke the inflammatory response depends on the neutrophils and leukocytes, reason why the neutrophil/lymphocyte (N/L) and mean platelet volume/platelet count (MPV/PC) indexes are considered to assess stroke. Aim: We aim to determine which index, N/L index or mean platelet volume/platelet count, is better to assess stroke in elderly. Methods: We retrospectively review files of patients over 65 years old with the previous stroke during the period of 2019-2022, including 180 patients (72 males 69-78 years and 108 females 67-84 years). All patients had brain imaging, initial and followup hematic cytometry to determine indexes and compare it between them. Results: Most patients had N/L < 3 (p = 0.045) and MPV/PC > 0.031 (p = 0.0021) during the first 48 h. The receiver operating characteristic showed area under the curve (AUC) values of MPV/PC = 0.872 (0.816-0.929) (p = 0.001) and N/L = 0.647 (0.564-0.730) (p = 0.001) with a significant difference between AUC values (p = 0.001). Conclusions: Mortality rises in 76-80 years group; males had a higher mortality in ischemic events compared to females. The MPV/PC is better to predict severe events and long hospital stay, which could be used as a prognosis during the first 48 h of hospitalization.
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| first_indexed | 2024-04-11T04:52:55Z |
| format | Article |
| id | doaj.art-14e01fca2ca44a43af3f574ffd5bdf11 |
| institution | Directory Open Access Journal |
| issn | 2462-4616 |
| language | English |
| last_indexed | 2024-04-11T04:52:55Z |
| publishDate | 2022-04-01 |
| publisher | Publicaciones Permanyer |
| record_format | Article |
| series | The Journal of Latin American Geriatric Medicine |
| spelling | doaj.art-14e01fca2ca44a43af3f574ffd5bdf112022-12-26T20:23:51ZengPublicaciones PermanyerThe Journal of Latin American Geriatric Medicine2462-46162022-04-018210.24875/LAGM.22000006Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference?Juan J. Gómez-Piña0Amairani Sierra-Hernández1Department of Internal Medicine, Speciality Hospital Dr. Antonio Fraga Mouret, National Medical Center La Raza, IMSS, Mexico City, MexicoDepartment of Internal Medicine, Speciality Hospital Dr. Antonio Fraga Mouret, National Medical Center La Raza, IMSS, Mexico City, MexicoIntroduction: In stroke the inflammatory response depends on the neutrophils and leukocytes, reason why the neutrophil/lymphocyte (N/L) and mean platelet volume/platelet count (MPV/PC) indexes are considered to assess stroke. Aim: We aim to determine which index, N/L index or mean platelet volume/platelet count, is better to assess stroke in elderly. Methods: We retrospectively review files of patients over 65 years old with the previous stroke during the period of 2019-2022, including 180 patients (72 males 69-78 years and 108 females 67-84 years). All patients had brain imaging, initial and followup hematic cytometry to determine indexes and compare it between them. Results: Most patients had N/L < 3 (p = 0.045) and MPV/PC > 0.031 (p = 0.0021) during the first 48 h. The receiver operating characteristic showed area under the curve (AUC) values of MPV/PC = 0.872 (0.816-0.929) (p = 0.001) and N/L = 0.647 (0.564-0.730) (p = 0.001) with a significant difference between AUC values (p = 0.001). Conclusions: Mortality rises in 76-80 years group; males had a higher mortality in ischemic events compared to females. The MPV/PC is better to predict severe events and long hospital stay, which could be used as a prognosis during the first 48 h of hospitalization. https://www.jgeriatricmedicine.com/frame_esp.php?id=74Mean platelet volume. Neutrophils/lymphocytes. Stroke. Mortality |
| spellingShingle | Juan J. Gómez-Piña Amairani Sierra-Hernández Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? The Journal of Latin American Geriatric Medicine Mean platelet volume. Neutrophils/lymphocytes. Stroke. Mortality |
| title | Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? |
| title_full | Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? |
| title_fullStr | Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? |
| title_full_unstemmed | Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? |
| title_short | Neutrophils/Lymphocytes and MPV/PC index assessed in stroke during elderly, is there a difference? |
| title_sort | neutrophils lymphocytes and mpv pc index assessed in stroke during elderly is there a difference |
| topic | Mean platelet volume. Neutrophils/lymphocytes. Stroke. Mortality |
| url | https://www.jgeriatricmedicine.com/frame_esp.php?id=74 |
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