MicroRNA-Mediated Regulation of ITGB3 and CHL1 Is Implicated in SSRI Action

MicroRNA-Mediated Regulation of ITGB3 and CHL1 Is Implicated in SSRI Action

Background: Selective serotonin reuptake inhibitor (SSRI) antidepressant drugs are the first-line of treatment for major depressive disorder (MDD) but are effective in <70% of patients. Our earlier genome-wide studies indicated that two genes encoding for cell adhesion proteins, close homolog...

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Bibliographic Details
Main Authors: Keren Oved, Luba Farberov, Avial Gilam, Ifat Israel, Danielle Haguel, David Gurwitz, Noam Shomron
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
ITGB3
CHL1
miR-221
miR-222
miR-151a-3p
selective serotonin reuptake inhibitors
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00355/full

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