Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients
Objective: The aim of this study was to evaluate acute cardiac remodeling after transcatheter closure of atrial septal defect (ASD) in adult patients. Methods: This study included 19 patients (40.0+-13.51 mean age) with secundum ASD who underwent successful transcatheter closure. All patients rece...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2015-04-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-57106 |
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| author | Kevser Gülcihan Balcı Mustafa Mücahit Balcı Muhammed Murat Aksoy Samet Yılmaz Mehmet Aytürk Mehmet Doğan Ekrem Yeter Ramazan Akdemir |
| author_facet | Kevser Gülcihan Balcı Mustafa Mücahit Balcı Muhammed Murat Aksoy Samet Yılmaz Mehmet Aytürk Mehmet Doğan Ekrem Yeter Ramazan Akdemir |
| author_sort | Kevser Gülcihan Balcı |
| collection | DOAJ |
| description | Objective: The aim of this study was to evaluate acute cardiac remodeling after transcatheter closure of atrial septal defect (ASD) in adult patients.
Methods: This study included 19 patients (40.0+-13.51 mean age) with secundum ASD who underwent successful transcatheter closure. All patients received routine transthoracic echocardiography, including tissue Doppler left ventricle (LV) and right ventricle (RV) myocardial performance indices (MPI), mitral annular plane systolic excursion (MAPSE) and tricuspid annular plane systolic excursion (TAPSE) before ASD closure, on first day, and at first and third months after closure.
Results: Left ventricle end-diastolic diameter (LVEDD) increased (37+-4 mm to 44+-5 mm, p<0.001); RVEDD decreased markedly after closure (40+-4 mm to 32+-5 mm, p<0.001); and differences existed in LV and RV adaptation. While MAPSE (1.87+-0.22 cm to 2.01+-0.23 cm, p<0.001) and LVMPI improved soon after procedure (0.44+-0.04 to 0.36+-0.03, p<0.001), RVMPI worsened until the first month post-procedure (0.25+-0.02 to 0.31+-0.03, p<0.001), but recovered by the third month follow-up visit (0.31+-0.03 to 0.27+-0.02, p<0.001). TAPSE remained unchanged (2.49+-0.46 cm to 2.51+-0.32 cm, p=0.078).
Conclusion: Closure of ASD using the Amplatzer Septal Occluder device led to a decrease in RV size and an increase in LV size. In the early period, while LV function improved, RV function deteriorated, probably due to RV functional and anatomical differences. |
| first_indexed | 2024-04-10T12:25:08Z |
| format | Article |
| id | doaj.art-14e17887c0f945a8b0a55d0f9b52d790 |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T12:25:08Z |
| publishDate | 2015-04-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-14e17887c0f945a8b0a55d0f9b52d7902023-02-15T16:15:12ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692015-04-0143325025810.5543/tkda.2015.57106TKDA-57106Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patientsKevser Gülcihan Balcı0Mustafa Mücahit Balcı1Muhammed Murat Aksoy2Samet Yılmaz3Mehmet Aytürk4Mehmet Doğan5Ekrem Yeter6Ramazan Akdemir7Turkiye Yuksek Ihtisas Research And Edücation Hospital, Cardiology Department, Ankara, TurkeyTurkiye Yuksek Ihtisas Research And Edücation Hospital, Cardiology Department, Ankara, TurkeySakarya University, Department of Cardiology,Sakarya,TURKEYTurkiye Yuksek Ihtisas Research And Edücation Hospital, Cardiology Department, Ankara, TurkeyKeciören Research And Edücation Hospital, Cardiology Department, Ankara, TurkeyDiskapi Yıldırım Beyazit Research And Edücation Hospital, Cardiology Department, Ankara, TurkeyDiskapi Yıldırım Beyazit Research And Edücation Hospital, Cardiology Department, Ankara, TurkeySakarya University, Department of Cardiology,Sakarya,TURKEYObjective: The aim of this study was to evaluate acute cardiac remodeling after transcatheter closure of atrial septal defect (ASD) in adult patients. Methods: This study included 19 patients (40.0+-13.51 mean age) with secundum ASD who underwent successful transcatheter closure. All patients received routine transthoracic echocardiography, including tissue Doppler left ventricle (LV) and right ventricle (RV) myocardial performance indices (MPI), mitral annular plane systolic excursion (MAPSE) and tricuspid annular plane systolic excursion (TAPSE) before ASD closure, on first day, and at first and third months after closure. Results: Left ventricle end-diastolic diameter (LVEDD) increased (37+-4 mm to 44+-5 mm, p<0.001); RVEDD decreased markedly after closure (40+-4 mm to 32+-5 mm, p<0.001); and differences existed in LV and RV adaptation. While MAPSE (1.87+-0.22 cm to 2.01+-0.23 cm, p<0.001) and LVMPI improved soon after procedure (0.44+-0.04 to 0.36+-0.03, p<0.001), RVMPI worsened until the first month post-procedure (0.25+-0.02 to 0.31+-0.03, p<0.001), but recovered by the third month follow-up visit (0.31+-0.03 to 0.27+-0.02, p<0.001). TAPSE remained unchanged (2.49+-0.46 cm to 2.51+-0.32 cm, p=0.078). Conclusion: Closure of ASD using the Amplatzer Septal Occluder device led to a decrease in RV size and an increase in LV size. In the early period, while LV function improved, RV function deteriorated, probably due to RV functional and anatomical differences.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-57106atrial septal defectechocardiography; left ventricle; right ventricle; ventricular remodeling |
| spellingShingle | Kevser Gülcihan Balcı Mustafa Mücahit Balcı Muhammed Murat Aksoy Samet Yılmaz Mehmet Aytürk Mehmet Doğan Ekrem Yeter Ramazan Akdemir Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients Türk Kardiyoloji Derneği Arşivi atrial septal defect echocardiography; left ventricle; right ventricle; ventricular remodeling |
| title | Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| title_full | Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| title_fullStr | Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| title_full_unstemmed | Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| title_short | Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| title_sort | remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients |
| topic | atrial septal defect echocardiography; left ventricle; right ventricle; ventricular remodeling |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-57106 |
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