Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasms

Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasms

Objectives: A mutation in the JAK2 gene, V617F, has been identified in several BCR-ABL1 negative myeloproliferative neoplasms (MPN): polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Defining the presence or absence of this mutation is an essential part of clin...

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Main Authors: Alline Didone, Luciana Nardinelli, Mariana Marchiani, Antonio Roberto Lancha Ruiz, Ariel Lais de Lima Costa, Ismael Severino Lima, Nathalia Moreira Santos, Sabri Saeed Sanabani, Israel Bendit
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Practical Laboratory Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235255171530007X

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