Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity

Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity

Abstract Background For centuries, microbial-based agents have been investigated as a therapeutic modality for the treatment of cancer. In theory, these methods would be cheap to produce, broadly applicable in a wide array of cancer types, and could synergize with other cancer treatment strategies....

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Bibliographic Details
Main Authors: Yu-Jui Kung, Brandon Lam, Ssu-Hsueh Tseng, Alana MacDonald, Hsin-Fang Tu, Suyang Wang, John Lin, Ya Chea Tsai, T. C. Wu, Chien-Fu Hung
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Biomedical Science
Subjects:
Colon cancer
Albumin
Interleukin-2 (IL-2)
Salmonella
Online Access:https://doi.org/10.1186/s12929-022-00841-y

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