Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life. Their toxic effects result from irreversible blockade of the enzymes acetylcholinesterase and butyrylcholinesterase, which causes overstimulation of the chol...

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Bibliographic Details
Main Authors:	Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Biomolecules
Subjects:	molecular modeling reactivators reactivation process organophosphates docking studies acetylcholinesterase
Online Access:	https://www.mdpi.com/2218-273X/11/2/169

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