A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity
Currently, there is growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related pathological complications. Antioxidants play an important role in human health and provide a defense against many...
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Format: | Article |
Language: | English |
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MDPI AG
2022-03-01
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Series: | Antioxidants |
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Online Access: | https://www.mdpi.com/2076-3921/11/3/584 |
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author | Irina Georgiana Munteanu Constantin Apetrei |
author_facet | Irina Georgiana Munteanu Constantin Apetrei |
author_sort | Irina Georgiana Munteanu |
collection | DOAJ |
description | Currently, there is growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related pathological complications. Antioxidants play an important role in human health and provide a defense against many diseases. Due to the valuable dietary role of these compounds, the analysis and determination of their amount in food is of particular importance. In recent years, many attempts have been made to provide simple, fast, and economical analytical approaches for the on-site detection and determination of antioxidant activity in food antioxidants. In this regard, electrochemical sensors and biosensors are considered promising tools for antioxidant research due to their high sensitivity, fast response time, and ease of miniaturization; thus, they are used in a variety of fields, including food analysis, drug screening, and toxicity research. Herein, we review the recent advances in sensors and biosensors for the detection of antioxidants, underlying principles, and emphasizing advantages, along with limitations regarding the ability to discriminate between the specific antioxidant or quantifying total antioxidant content. In this work, both direct and indirect methods for antioxidants detecting with electrochemical sensors and biosensors are analyzed in detail. This review aims to prove how electrochemical sensors and biosensors represent reliable alternatives to conventional methods for antioxidant analysis. |
first_indexed | 2024-03-09T13:51:46Z |
format | Article |
id | doaj.art-14ef01f1b8f04d0cbcae28b2ccbfff9f |
institution | Directory Open Access Journal |
issn | 2076-3921 |
language | English |
last_indexed | 2024-03-09T13:51:46Z |
publishDate | 2022-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Antioxidants |
spelling | doaj.art-14ef01f1b8f04d0cbcae28b2ccbfff9f2023-11-30T20:48:06ZengMDPI AGAntioxidants2076-39212022-03-0111358410.3390/antiox11030584A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant ActivityIrina Georgiana Munteanu0Constantin Apetrei1Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaCurrently, there is growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related pathological complications. Antioxidants play an important role in human health and provide a defense against many diseases. Due to the valuable dietary role of these compounds, the analysis and determination of their amount in food is of particular importance. In recent years, many attempts have been made to provide simple, fast, and economical analytical approaches for the on-site detection and determination of antioxidant activity in food antioxidants. In this regard, electrochemical sensors and biosensors are considered promising tools for antioxidant research due to their high sensitivity, fast response time, and ease of miniaturization; thus, they are used in a variety of fields, including food analysis, drug screening, and toxicity research. Herein, we review the recent advances in sensors and biosensors for the detection of antioxidants, underlying principles, and emphasizing advantages, along with limitations regarding the ability to discriminate between the specific antioxidant or quantifying total antioxidant content. In this work, both direct and indirect methods for antioxidants detecting with electrochemical sensors and biosensors are analyzed in detail. This review aims to prove how electrochemical sensors and biosensors represent reliable alternatives to conventional methods for antioxidant analysis.https://www.mdpi.com/2076-3921/11/3/584antioxidant activitysensorsbiosensorsenzymesDNA |
spellingShingle | Irina Georgiana Munteanu Constantin Apetrei A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity Antioxidants antioxidant activity sensors biosensors enzymes DNA |
title | A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity |
title_full | A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity |
title_fullStr | A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity |
title_full_unstemmed | A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity |
title_short | A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity |
title_sort | review on electrochemical sensors and biosensors used in assessing antioxidant activity |
topic | antioxidant activity sensors biosensors enzymes DNA |
url | https://www.mdpi.com/2076-3921/11/3/584 |
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