Exposure to Secondhand Smoke Extract Increases Cisplatin Resistance in Head and Neck Cancer Cells

Exposure to Secondhand Smoke Extract Increases Cisplatin Resistance in Head and Neck Cancer Cells

Chemotherapy and radiotherapy resistance are major obstacles in the long-term efficacy of head and neck squamous cell carcinoma (HNSCC) treatment. Secondhand smoke (SHS) exposure is common and has been proposed as an independent predictor of HNSCC recurrence and disease-free survival. However, the u...

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Bibliographic Details
Main Authors: Balaji Sadhasivam, Jimmy Manyanga, Vengatesh Ganapathy, Pawan Acharya, Célia Bouharati, Mayilvanan Chinnaiyan, Toral Mehta, Basil Mathews, Samuel Castles, David A. Rubenstein, Alayna P. Tackett, Yan D. Zhao, Ilangovan Ramachandran, Lurdes Queimado
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
head and neck squamous cell carcinoma (HNSCC)
oral cancer
response to therapy
secondhand smoke
IC<sub>50</sub>
multidrug resistance
Online Access:https://www.mdpi.com/1422-0067/25/2/1032

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