Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods
Objectives: The bioavailability of dietary iron present in a nutritional formulation may be evaluated by in vitro and in vivo methods since they provide for a cohesive line study and provided in the literature. The aim of this study was to evaluate the bioavailability of iron targeting a comparative...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Arán Ediciones, S. L.
2013-02-01
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| Series: | Nutrición Hospitalaria |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000100012&lng=en&tlng=en |
| _version_ | 1818431588003741696 |
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| author | Luciana Bueno Juliana C. Pizzo Osvaldo Freitas Fernando Barbosa Junior José Ernesto dos Santos Julio Sergio Marchini José Eduardo Dutra-de-Oliveira |
| author_facet | Luciana Bueno Juliana C. Pizzo Osvaldo Freitas Fernando Barbosa Junior José Ernesto dos Santos Julio Sergio Marchini José Eduardo Dutra-de-Oliveira |
| author_sort | Luciana Bueno |
| collection | DOAJ |
| description | Objectives: The bioavailability of dietary iron present in a nutritional formulation may be evaluated by in vitro and in vivo methods since they provide for a cohesive line study and provided in the literature. The aim of this study was to evaluate the bioavailability of iron targeting a comparative analysis of two nutritional supplement formulations (A and B). Methods: For this study were using in vitro and in vivo methods, both described in the literature for availability of iron in an enteral feeding after ingestion supplement nutrition with much nutrients. Results: The results obtained by in vitro simulation of the human gastrointestinal tract were 0.70 ± 0.02 and 0.80 ± 0.01 % iron availability by formulations A and B. In vivo studies, as measured by the curves of serum iron in humans after ingestion of formulations allowed the calculation of coefficient of variation Δ < 0, indicating that there was a low absorption of iron. The bioavailability of iron as two multinutrients solutions obtained by in vitro and in vivo showed that there were comparisons of those methodologies used in this study. |
| first_indexed | 2024-12-14T15:51:41Z |
| format | Article |
| id | doaj.art-14f37cccf4c54916b841955b13021b76 |
| institution | Directory Open Access Journal |
| issn | 0212-1611 |
| language | English |
| last_indexed | 2024-12-14T15:51:41Z |
| publishDate | 2013-02-01 |
| publisher | Arán Ediciones, S. L. |
| record_format | Article |
| series | Nutrición Hospitalaria |
| spelling | doaj.art-14f37cccf4c54916b841955b13021b762022-12-21T22:55:21ZengArán Ediciones, S. L.Nutrición Hospitalaria0212-16112013-02-01281939910.3305/nh.2013.28.1.5965S0212-16112013000100012Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methodsLuciana Bueno0Juliana C. Pizzo1Osvaldo Freitas2Fernando Barbosa Junior3José Ernesto dos Santos4Julio Sergio Marchini5José Eduardo Dutra-de-Oliveira6Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloObjectives: The bioavailability of dietary iron present in a nutritional formulation may be evaluated by in vitro and in vivo methods since they provide for a cohesive line study and provided in the literature. The aim of this study was to evaluate the bioavailability of iron targeting a comparative analysis of two nutritional supplement formulations (A and B). Methods: For this study were using in vitro and in vivo methods, both described in the literature for availability of iron in an enteral feeding after ingestion supplement nutrition with much nutrients. Results: The results obtained by in vitro simulation of the human gastrointestinal tract were 0.70 ± 0.02 and 0.80 ± 0.01 % iron availability by formulations A and B. In vivo studies, as measured by the curves of serum iron in humans after ingestion of formulations allowed the calculation of coefficient of variation Δ < 0, indicating that there was a low absorption of iron. The bioavailability of iron as two multinutrients solutions obtained by in vitro and in vivo showed that there were comparisons of those methodologies used in this study.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000100012&lng=en&tlng=enBiodisponibilidadHierroIn vitroIn vivo |
| spellingShingle | Luciana Bueno Juliana C. Pizzo Osvaldo Freitas Fernando Barbosa Junior José Ernesto dos Santos Julio Sergio Marchini José Eduardo Dutra-de-Oliveira Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods Nutrición Hospitalaria Biodisponibilidad Hierro In vitro In vivo |
| title | Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods |
| title_full | Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods |
| title_fullStr | Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods |
| title_full_unstemmed | Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods |
| title_short | Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods |
| title_sort | bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo a comparative methodology between methods |
| topic | Biodisponibilidad Hierro In vitro In vivo |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000100012&lng=en&tlng=en |
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