Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study
Introduction: Coronavirus Disease 2019 (COVID-19) is a highly infectious disease primarily characterised by respiratory symptoms. While respiratory symptoms initially predominated during the pandemic, there has been an increase in Gastrointestinal (GI) manifestations in the later phase. Moreover...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2023-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18852/66018_CE[Ra1]_F(IS)_QC&PAT(KK_RN_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdf |
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| author | Sri Vengadesh Gopal Ray Ganapathy Saravanan Pandian Renuka Srisai Peddireddi |
| author_facet | Sri Vengadesh Gopal Ray Ganapathy Saravanan Pandian Renuka Srisai Peddireddi |
| author_sort | Sri Vengadesh Gopal |
| collection | DOAJ |
| description | Introduction: Coronavirus Disease 2019 (COVID-19) is a
highly infectious disease primarily characterised by respiratory
symptoms. While respiratory symptoms initially predominated
during the pandemic, there has been an increase in
Gastrointestinal (GI) manifestations in the later phase. Moreover,
reports have highlighted the presence of chronic GI symptoms
following COVID-19 infection.
Aim: To determine the prevalence of GI sequelae after COVID-19
hospitalisation and its association with Computed Tomography
(CT) chest severity scores.
Materials and Methods: The present cross-sectional study was
conducted at a COVID-19 designated tertiary care hospital, Indira
Gandhi Medical College and Research Institute, Puducherry,
India, from April 2022 to December 2022. Patients admitted with
COVID-19 illness between January 2021 and June 2021 were
included in the study. Socio-demographic details, CT chest
severity scores, and chronic GI symptoms (nausea, vomiting,
diarrhoea, abdominal pain, etc.) were collected from patients’
medical records and through telephonic interviews. The data
were analysed using Statistical Package for Social Sciences
(SPSS) version 26.0 Qualitative variables were expressed as
frequencies and percentages. The association of CT severity
with GI symptoms was assessed using the Chi-square test, with
a p-value of <0.05 considered significant.
Results: A total of 1,903 patients who met the inclusion criteria
were included in the study. Among the participants, 1142
(60%) were males and 761 (40%) were females. The majority
of patients belonged to the age group of 41-60 years, followed
by 21-40 years. The mean age of the patients was 48.88±1.72
years. The prevalence of chronic GI symptoms was observed in
26% of patients, with 36.6% experiencing abdominal pain and
19.6% having gastroesophageal reflux. Diarrhoea was reported
by 15.8% of patients. Patients with severe CT severity scores
showed a lower prevalence of GI symptoms.
Conclusion: Chronic GI symptoms were observed in nearly onefourth of the patients hospitalised for COVID-19. Interestingly,
patients with severe CT chest severity scores exhibited a lower
prevalence of GI symptoms. Further experimental studies are
needed to understand the pathogenesis of GI symptoms and
their association with CT severity, which could contribute to the
development of effective treatment strategies. |
| first_indexed | 2024-03-08T19:23:10Z |
| format | Article |
| id | doaj.art-14f4879132e046b1b703055b5f4050f0 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-08T19:23:10Z |
| publishDate | 2023-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-14f4879132e046b1b703055b5f4050f02023-12-26T11:50:29ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-12-011712232510.7860/JCDR/2023/66018.18852Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional StudySri Vengadesh Gopal0Ray Ganapathy1Saravanan Pandian2Renuka Srisai Peddireddi3Associate Professor, Department of General Surgery, Indira Gandhi Medical College and Research Institute, Puducherry, India.Associate Professor, Department of General Surgery, Indira Gandhi Medical College and Research Institute, Puducherry, India.Assistant Professor, Department of General Surgery, Indira Gandhi Medical College and Research Institute, Puducherry, India.Junior Resident, Department of General Surgery, Indira Gandhi Medical College and Research Institute, Puducherry, India.Introduction: Coronavirus Disease 2019 (COVID-19) is a highly infectious disease primarily characterised by respiratory symptoms. While respiratory symptoms initially predominated during the pandemic, there has been an increase in Gastrointestinal (GI) manifestations in the later phase. Moreover, reports have highlighted the presence of chronic GI symptoms following COVID-19 infection. Aim: To determine the prevalence of GI sequelae after COVID-19 hospitalisation and its association with Computed Tomography (CT) chest severity scores. Materials and Methods: The present cross-sectional study was conducted at a COVID-19 designated tertiary care hospital, Indira Gandhi Medical College and Research Institute, Puducherry, India, from April 2022 to December 2022. Patients admitted with COVID-19 illness between January 2021 and June 2021 were included in the study. Socio-demographic details, CT chest severity scores, and chronic GI symptoms (nausea, vomiting, diarrhoea, abdominal pain, etc.) were collected from patients’ medical records and through telephonic interviews. The data were analysed using Statistical Package for Social Sciences (SPSS) version 26.0 Qualitative variables were expressed as frequencies and percentages. The association of CT severity with GI symptoms was assessed using the Chi-square test, with a p-value of <0.05 considered significant. Results: A total of 1,903 patients who met the inclusion criteria were included in the study. Among the participants, 1142 (60%) were males and 761 (40%) were females. The majority of patients belonged to the age group of 41-60 years, followed by 21-40 years. The mean age of the patients was 48.88±1.72 years. The prevalence of chronic GI symptoms was observed in 26% of patients, with 36.6% experiencing abdominal pain and 19.6% having gastroesophageal reflux. Diarrhoea was reported by 15.8% of patients. Patients with severe CT severity scores showed a lower prevalence of GI symptoms. Conclusion: Chronic GI symptoms were observed in nearly onefourth of the patients hospitalised for COVID-19. Interestingly, patients with severe CT chest severity scores exhibited a lower prevalence of GI symptoms. Further experimental studies are needed to understand the pathogenesis of GI symptoms and their association with CT severity, which could contribute to the development of effective treatment strategies.https://www.jcdr.net/articles/PDF/18852/66018_CE[Ra1]_F(IS)_QC&PAT(KK_RN_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdfcoronavirusinfectionpandemictomography |
| spellingShingle | Sri Vengadesh Gopal Ray Ganapathy Saravanan Pandian Renuka Srisai Peddireddi Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study Journal of Clinical and Diagnostic Research coronavirus infection pandemic tomography |
| title | Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study |
| title_full | Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study |
| title_fullStr | Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study |
| title_full_unstemmed | Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study |
| title_short | Prevalence of Gastrointestinal Sequelae among Previously Hospitalised Patients due to COVID-19 and its Association with Computed Tomography Chest Severity: A Cross-sectional Study |
| title_sort | prevalence of gastrointestinal sequelae among previously hospitalised patients due to covid 19 and its association with computed tomography chest severity a cross sectional study |
| topic | coronavirus infection pandemic tomography |
| url | https://www.jcdr.net/articles/PDF/18852/66018_CE[Ra1]_F(IS)_QC&PAT(KK_RN_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdf |
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