Over-Expression of βII-Tubulin and Especially Its Localization in Cell Nuclei Correlates with Poorer Outcomes in Colorectal Cancer
Tubulin is a heterodimer of α and β subunits, both existing as isotypes differing in amino acid sequence encoded by different genes. Specific isotypes of tubulin have associations with cancer that are not well understood. Previous studies found that βII-tubulin is express...
Main Authors: | Kseniya Ruksha, Artur Mezheyeuski, Alexander Nerovnya, Tatyana Bich, Gennady Tur, Julia Gorgun, Richard Luduena, Anna Portyanko |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
|
Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/8/1/25 |
Similar Items
-
Reconstituting Microtubules: A Decades-Long Effort From Building Block Identification to the Generation of Recombinant α/β-Tubulin
by: Shih-Chieh Ti
Published: (2022-04-01) -
Deciphering the Tubulin Language: Molecular Determinants and Readout Mechanisms of the Tubulin Code in Neurons
by: Riccardo Zocchi, et al.
Published: (2023-02-01) -
Tubulin Resists Degradation by Cereblon-Recruiting PROTACs
by: Ivana Gasic, et al.
Published: (2020-04-01) -
The Tubulin Code and Tubulin-Modifying Enzymes in Autophagy and Cancer
by: Daniela Trisciuoglio, et al.
Published: (2021-12-01) -
The Tubulin Code in Mitosis and Cancer
by: Danilo Lopes, et al.
Published: (2020-10-01)