Human_SNP_TATAdb: a database of SNPs that statistically significantly change the affinity of the TATA-binding protein to human gene promoters: genome-wide analysis and use cases

Human_SNP_TATAdb: a database of SNPs that statistically significantly change the affinity of the TATA-binding protein to human gene promoters: genome-wide analysis and use cases

It was previously shown that the expression levels of human genes positively correlate with TBP affinity for the promoters of these genes. In turn, single nucleotide polymorphisms (SNPs) in human gene promoters can affect TBP affinity for DNA and, as a consequence, gene expression. The Institute of...

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Bibliographic Details
Main Authors: S. V. Filonov, N. L. Podkolodnyy, O. A. Podkolodnaya, N. N. Tverdokhleb, P. M. Ponomarenko, D. A. Rasskazov, A. G. Bogomolov, M. P. Ponomarenko
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2023-12-01
Series:Вавиловский журнал генетики и селекции
Subjects:
tata box
affinity
tbp
single nucleotide polymorphism
database
genome-wide analysis
Online Access:https://vavilov.elpub.ru/jour/article/view/3972

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