The role of infectious stimulus in the initiation and immune inflammation in psoriasis
Psoriasis is a common skin disease in which the development of the decisive role played by genetic and environmental factors. Many of the candidate genes linked with psoriasis, are directly related to acquired or congenital defects of the immune system, epithelial barrier permeability of the intesti...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Saratov State Medical University
2014-09-01
|
| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2014_03-01_530-537.pdf |
| _version_ | 1818837511310409728 |
|---|---|
| author | Slesarenko N.A. Utz S.R. Kulaev K.A. Resnikova M.A. Panina L.V. Popova O.V. |
| author_facet | Slesarenko N.A. Utz S.R. Kulaev K.A. Resnikova M.A. Panina L.V. Popova O.V. |
| author_sort | Slesarenko N.A. |
| collection | DOAJ |
| description | Psoriasis is a common skin disease in which the development of the decisive role played by genetic and environmental factors. Many of the candidate genes linked with psoriasis, are directly related to acquired or congenital defects of the immune system, epithelial barrier permeability of the intestinal wall, and the keratinocyte membrain. Formation of an immune response to Th-1 type high expression and activity of antimicrobial peptides like state at their potential infection. This review discusses the possible immune mechanisms are involved in the relationship between infection and disease process in psoriatic skin. We survey the literature and discuss the suitability of infection factors in treatment modality for psoriasis. |
| first_indexed | 2024-12-19T03:23:40Z |
| format | Article |
| id | doaj.art-14fa07227d32433a8bce287561925c23 |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-19T03:23:40Z |
| publishDate | 2014-09-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-14fa07227d32433a8bce287561925c232022-12-21T20:37:42ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182014-09-011035305373805The role of infectious stimulus in the initiation and immune inflammation in psoriasisSlesarenko N.A.0Utz S.R.1Kulaev K.A.2Resnikova M.A.3Panina L.V.4Popova O.V.5Saratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversityPsoriasis is a common skin disease in which the development of the decisive role played by genetic and environmental factors. Many of the candidate genes linked with psoriasis, are directly related to acquired or congenital defects of the immune system, epithelial barrier permeability of the intestinal wall, and the keratinocyte membrain. Formation of an immune response to Th-1 type high expression and activity of antimicrobial peptides like state at their potential infection. This review discusses the possible immune mechanisms are involved in the relationship between infection and disease process in psoriatic skin. We survey the literature and discuss the suitability of infection factors in treatment modality for psoriasis.http://www.ssmj.ru/system/files/2014_03-01_530-537.pdfantimicrobial peptidesendotoxinimmune responsemicrobial factorspsoriasisstreptococcal superantigens |
| spellingShingle | Slesarenko N.A. Utz S.R. Kulaev K.A. Resnikova M.A. Panina L.V. Popova O.V. The role of infectious stimulus in the initiation and immune inflammation in psoriasis Саратовский научно-медицинский журнал antimicrobial peptides endotoxin immune response microbial factors psoriasis streptococcal superantigens |
| title | The role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| title_full | The role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| title_fullStr | The role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| title_full_unstemmed | The role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| title_short | The role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| title_sort | role of infectious stimulus in the initiation and immune inflammation in psoriasis |
| topic | antimicrobial peptides endotoxin immune response microbial factors psoriasis streptococcal superantigens |
| url | http://www.ssmj.ru/system/files/2014_03-01_530-537.pdf |
| work_keys_str_mv | AT slesarenkona theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT utzsr theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT kulaevka theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT resnikovama theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT paninalv theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT popovaov theroleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT slesarenkona roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT utzsr roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT kulaevka roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT resnikovama roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT paninalv roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis AT popovaov roleofinfectiousstimulusintheinitiationandimmuneinflammationinpsoriasis |