Head and neck carcinoma in children: A clinicopathological study of 42 cases
Background/purpose: Cancer is an important part of the global burden of childhood diseases. Head and neck carcinoma in children is rare and related research is limited. This study aimed to investigate the clinicopathological features of childhood head and neck carcinoma. Materials and methods: Forty...
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Format: | Article |
Language: | English |
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Elsevier
2023-10-01
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Series: | Journal of Dental Sciences |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1991790223001228 |
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author | Xin-Jia Cai Zu-Nan Tang Yu-Ping Liu Xu Wang Jia-Ying Bai Xiao-Wen Guo He-Yu Zhang Jian-Yun Zhang Tie-Jun Li |
author_facet | Xin-Jia Cai Zu-Nan Tang Yu-Ping Liu Xu Wang Jia-Ying Bai Xiao-Wen Guo He-Yu Zhang Jian-Yun Zhang Tie-Jun Li |
author_sort | Xin-Jia Cai |
collection | DOAJ |
description | Background/purpose: Cancer is an important part of the global burden of childhood diseases. Head and neck carcinoma in children is rare and related research is limited. This study aimed to investigate the clinicopathological features of childhood head and neck carcinoma. Materials and methods: Forty-two cases of childhood head and neck carcinoma treated in our institution were reviewed and analyzed. Results: Median age overall was 11 years. Twenty-three patients (54.8%) were male and 19 (45.2%) were female. Parotid gland location was most common (54.8%). Mucoepidermoid carcinoma and squamous cell carcinoma were the most common histological types (57.1% and 11.9%, respectively). Two patients had a history of bone marrow transplantation and two had a history of odontogenic keratocyst. The recurrence rate after treatment was 8.6%. Conclusion: Early diagnosis and treatment and close follow-up of childhood head and neck carcinoma are warranted to prevent recurrence and improve clinical outcome. |
first_indexed | 2024-03-11T21:34:29Z |
format | Article |
id | doaj.art-15051fa670a041db9ada459554b2baa6 |
institution | Directory Open Access Journal |
issn | 1991-7902 |
language | English |
last_indexed | 2024-03-11T21:34:29Z |
publishDate | 2023-10-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Dental Sciences |
spelling | doaj.art-15051fa670a041db9ada459554b2baa62023-09-27T04:42:25ZengElsevierJournal of Dental Sciences1991-79022023-10-0118414861492Head and neck carcinoma in children: A clinicopathological study of 42 casesXin-Jia Cai0Zu-Nan Tang1Yu-Ping Liu2Xu Wang3Jia-Ying Bai4Xiao-Wen Guo5He-Yu Zhang6Jian-Yun Zhang7Tie-Jun Li8Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), Beijing, PR China; Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaDepartment of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaDepartment of Oral Medicine, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaDepartment of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaDepartment of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR ChinaCentral Laboratory, Peking University School and Hospital of Stomatology, Beijing, PR ChinaDepartment of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR China; Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), Beijing, PR China; Corresponding author. Department of Oral Pathology, Peking University School and Hospital of Stomatology, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, PR China.Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), Beijing, PR China; Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, PR China; Corresponding author. Department of Oral Pathology, Peking University School and Hospital of Stomatology, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, PR China.Background/purpose: Cancer is an important part of the global burden of childhood diseases. Head and neck carcinoma in children is rare and related research is limited. This study aimed to investigate the clinicopathological features of childhood head and neck carcinoma. Materials and methods: Forty-two cases of childhood head and neck carcinoma treated in our institution were reviewed and analyzed. Results: Median age overall was 11 years. Twenty-three patients (54.8%) were male and 19 (45.2%) were female. Parotid gland location was most common (54.8%). Mucoepidermoid carcinoma and squamous cell carcinoma were the most common histological types (57.1% and 11.9%, respectively). Two patients had a history of bone marrow transplantation and two had a history of odontogenic keratocyst. The recurrence rate after treatment was 8.6%. Conclusion: Early diagnosis and treatment and close follow-up of childhood head and neck carcinoma are warranted to prevent recurrence and improve clinical outcome.http://www.sciencedirect.com/science/article/pii/S1991790223001228Head and neck carcinomaMucoepidermoid carcinomaSquamous cell carcinomaChildren |
spellingShingle | Xin-Jia Cai Zu-Nan Tang Yu-Ping Liu Xu Wang Jia-Ying Bai Xiao-Wen Guo He-Yu Zhang Jian-Yun Zhang Tie-Jun Li Head and neck carcinoma in children: A clinicopathological study of 42 cases Journal of Dental Sciences Head and neck carcinoma Mucoepidermoid carcinoma Squamous cell carcinoma Children |
title | Head and neck carcinoma in children: A clinicopathological study of 42 cases |
title_full | Head and neck carcinoma in children: A clinicopathological study of 42 cases |
title_fullStr | Head and neck carcinoma in children: A clinicopathological study of 42 cases |
title_full_unstemmed | Head and neck carcinoma in children: A clinicopathological study of 42 cases |
title_short | Head and neck carcinoma in children: A clinicopathological study of 42 cases |
title_sort | head and neck carcinoma in children a clinicopathological study of 42 cases |
topic | Head and neck carcinoma Mucoepidermoid carcinoma Squamous cell carcinoma Children |
url | http://www.sciencedirect.com/science/article/pii/S1991790223001228 |
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