Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study
Background and aims: The ability to safely and effectively obtain sufficient tissue for pathologic evaluation by using endoscopic ultrasound (EUS) guidance remains a challenge. Novel designs in EUS needles may provide for improved ability to obtain such core biopsies. The aim of this study was to ev...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2016-08-01
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| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-112581 |
| _version_ | 1818962090836099072 |
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| author | Christopher J. DiMaio Jennifer M. Kolb Petros C. Benias Hiral Shah Shashin Shah Oleh Haluszka Jennifer Maranki Kaveh Sharzehi Eric Lam Stuart R. Gordon Sarah M. Hyder Pavlos Z. Kaimakliotis Satya B. Allaparthi Frank G. Gress Amrita Sethi Ashish R. Shah Jose Nieto Vivek Kaul Shivangi Kothari Truptesh H. Kothari Sammy Ho Manhal J. Izzy Neil R. Sharma Rabindra R. Watson V. Raman Muthusamy Douglas K. Pleskow Tyler M. Berzin Mandeep Sawhney Emad Aljahdi Marvin Ryou Clarence K. Wong Parantap Gupta Dennis Yang Susana Gonzalez Douglas G. Adler |
| author_facet | Christopher J. DiMaio Jennifer M. Kolb Petros C. Benias Hiral Shah Shashin Shah Oleh Haluszka Jennifer Maranki Kaveh Sharzehi Eric Lam Stuart R. Gordon Sarah M. Hyder Pavlos Z. Kaimakliotis Satya B. Allaparthi Frank G. Gress Amrita Sethi Ashish R. Shah Jose Nieto Vivek Kaul Shivangi Kothari Truptesh H. Kothari Sammy Ho Manhal J. Izzy Neil R. Sharma Rabindra R. Watson V. Raman Muthusamy Douglas K. Pleskow Tyler M. Berzin Mandeep Sawhney Emad Aljahdi Marvin Ryou Clarence K. Wong Parantap Gupta Dennis Yang Susana Gonzalez Douglas G. Adler |
| author_sort | Christopher J. DiMaio |
| collection | DOAJ |
| description | Background and aims: The ability to safely and effectively obtain sufficient tissue for pathologic evaluation by using endoscopic ultrasound (EUS) guidance remains a challenge. Novel designs in EUS needles may provide for improved ability to obtain such core biopsies. The aim of this study was to evaluate the diagnostic yield of core biopsy specimens obtained using a novel EUS needle specifically designed to obtain core biopsies.
Patients and methods: Multicenter retrospective review of all EUS-guided fine-needle biopsies obtained using a novel biopsy needle (SharkCore FNB needle, Medtronic, Dublin, Ireland). Data regarding patient demographics, lesion type/location, technical parameters, and diagnostic yield was obtained.
Results: A total of 250 lesions were biopsied in 226 patients (Median age 66 years; 113 (50 %) male). Median size of all lesions (mm): 26 (2 – 150). Overall, a cytologic diagnosis was rendered in 81 % specimens with a median number of 3 passes. When rapid onsite cytologic evaluation (ROSE) was used, cytologic diagnostic yield was 126/149 (85 %) with a median number of 3 passes; without ROSE, cytologic diagnostic yield was 31/45 (69 %, P = 0.03) with a median number of 3 passes. Overall, a pathologic diagnosis was rendered in 130/147 (88 %) specimens with a median number of 2 passes. Pathologic diagnostic yield for specific lesion types: pancreas 70/81 (86 %), subepithelial lesion 13/15 (87 %), lymph node 26/28 (93 %). Ten patients (10/226, 4 %) experienced adverse events: 4 acute pancreatitis, 5 pain, 1 fever/cholangitis.
Conclusions: Initial experience with a novel EUS core biopsy needle demonstrates excellent pathologic diagnostic yield with a minimum number of passes. |
| first_indexed | 2024-12-20T12:23:48Z |
| format | Article |
| id | doaj.art-1506c9e0aeba4e6881a0faad4150673f |
| institution | Directory Open Access Journal |
| issn | 2364-3722 2196-9736 |
| language | English |
| last_indexed | 2024-12-20T12:23:48Z |
| publishDate | 2016-08-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Endoscopy International Open |
| spelling | doaj.art-1506c9e0aeba4e6881a0faad4150673f2022-12-21T19:40:54ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362016-08-010409E974E97910.1055/s-0042-112581Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter studyChristopher J. DiMaio0Jennifer M. Kolb1Petros C. Benias2Hiral Shah3Shashin Shah4Oleh Haluszka5Jennifer Maranki6Kaveh Sharzehi7Eric Lam8Stuart R. Gordon9Sarah M. Hyder10Pavlos Z. Kaimakliotis11Satya B. Allaparthi12Frank G. Gress13Amrita Sethi14Ashish R. Shah15Jose Nieto16Vivek Kaul17Shivangi Kothari18Truptesh H. Kothari19Sammy Ho20Manhal J. Izzy21Neil R. Sharma22Rabindra R. Watson23V. Raman Muthusamy24Douglas K. Pleskow25Tyler M. Berzin26Mandeep Sawhney27Emad Aljahdi28Marvin Ryou29Clarence K. Wong30Parantap Gupta31Dennis Yang32Susana Gonzalez33Douglas G. Adler34Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, New York, New York, United StatesDr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, New York, New York, United StatesMount Sinai Beth Israel Medical Center, New York, New York, United StatesLehigh Valley Hospital, Allentown, Pennsylvania, United StatesLehigh Valley Hospital, Allentown, Pennsylvania, United StatesTemple University School of Medicine, Philadelphia, Pennsylvania, United StatesTemple University School of Medicine, Philadelphia, Pennsylvania, United StatesTemple University School of Medicine, Philadelphia, Pennsylvania, United StatesUniversity of British Columbia, Vancouver, British Columbia, CanadaDartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United StatesDartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United StatesLahey Clinic, Burlington, Massachusetts, United StatesLahey Clinic, Burlington, Massachusetts, United StatesNewYork-Presbyterian Hospital/Columbia University, New York, New York, United StatesNewYork-Presbyterian Hospital/Columbia University, New York, New York, United StatesNewYork-Presbyterian Hospital/Columbia University, New York, New York, United StatesBorland-Groover Clinic, Jacksonville, Florida, United StatesUniversity of Rochester Medical Center, Rochester, New York, United StatesUniversity of Rochester Medical Center, Rochester, New York, United StatesUniversity of Rochester Medical Center, Rochester, New York, United StatesMontefiore Medical Center, Bronx, New York, United StatesMontefiore Medical Center, Bronx, New York, United StatesParkview Health System, Wayne, Indiana, United StatesDavid Geffen School of Medicine at UCLA, Los Angeles, California, United StatesDavid Geffen School of Medicine at UCLA, Los Angeles, California, United StatesBeth Israel Deaconess Medical Center, Boston, Massachusetts, United StatesBeth Israel Deaconess Medical Center, Boston, Massachusetts, United StatesBeth Israel Deaconess Medical Center, Boston, Massachusetts, United StatesBeth Israel Deaconess Medical Center, Boston, Massachusetts, United StatesBrigham and Women’s Hospital, Boston, Massachusetts, United StatesUniversity of Alberta, Edmonton, Alberta, CanadaCrystal Run Healthcare, Middletown, New York, United StatesDr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, New York, New York, United StatesDr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, New York, New York, United StatesUniversity of Utah School of Medicine, Salt Lake City, Utah, United StatesBackground and aims: The ability to safely and effectively obtain sufficient tissue for pathologic evaluation by using endoscopic ultrasound (EUS) guidance remains a challenge. Novel designs in EUS needles may provide for improved ability to obtain such core biopsies. The aim of this study was to evaluate the diagnostic yield of core biopsy specimens obtained using a novel EUS needle specifically designed to obtain core biopsies. Patients and methods: Multicenter retrospective review of all EUS-guided fine-needle biopsies obtained using a novel biopsy needle (SharkCore FNB needle, Medtronic, Dublin, Ireland). Data regarding patient demographics, lesion type/location, technical parameters, and diagnostic yield was obtained. Results: A total of 250 lesions were biopsied in 226 patients (Median age 66 years; 113 (50 %) male). Median size of all lesions (mm): 26 (2 – 150). Overall, a cytologic diagnosis was rendered in 81 % specimens with a median number of 3 passes. When rapid onsite cytologic evaluation (ROSE) was used, cytologic diagnostic yield was 126/149 (85 %) with a median number of 3 passes; without ROSE, cytologic diagnostic yield was 31/45 (69 %, P = 0.03) with a median number of 3 passes. Overall, a pathologic diagnosis was rendered in 130/147 (88 %) specimens with a median number of 2 passes. Pathologic diagnostic yield for specific lesion types: pancreas 70/81 (86 %), subepithelial lesion 13/15 (87 %), lymph node 26/28 (93 %). Ten patients (10/226, 4 %) experienced adverse events: 4 acute pancreatitis, 5 pain, 1 fever/cholangitis. Conclusions: Initial experience with a novel EUS core biopsy needle demonstrates excellent pathologic diagnostic yield with a minimum number of passes.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-112581 |
| spellingShingle | Christopher J. DiMaio Jennifer M. Kolb Petros C. Benias Hiral Shah Shashin Shah Oleh Haluszka Jennifer Maranki Kaveh Sharzehi Eric Lam Stuart R. Gordon Sarah M. Hyder Pavlos Z. Kaimakliotis Satya B. Allaparthi Frank G. Gress Amrita Sethi Ashish R. Shah Jose Nieto Vivek Kaul Shivangi Kothari Truptesh H. Kothari Sammy Ho Manhal J. Izzy Neil R. Sharma Rabindra R. Watson V. Raman Muthusamy Douglas K. Pleskow Tyler M. Berzin Mandeep Sawhney Emad Aljahdi Marvin Ryou Clarence K. Wong Parantap Gupta Dennis Yang Susana Gonzalez Douglas G. Adler Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study Endoscopy International Open |
| title | Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study |
| title_full | Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study |
| title_fullStr | Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study |
| title_full_unstemmed | Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study |
| title_short | Initial experience with a novel EUS-guided core biopsy needle (SharkCore): results of a large North American multicenter study |
| title_sort | initial experience with a novel eus guided core biopsy needle sharkcore results of a large north american multicenter study |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-112581 |
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