Genetic variant in MTRR, but not MTR, is associated with risk of congenital heart disease: an integrated meta-analysis.

Genetic variant in MTRR, but not MTR, is associated with risk of congenital heart disease: an integrated meta-analysis.

BACKGROUND: Congenital heart disease (CHD) is one of the most common birth defects and the leading cause of deaths among individuals with congenital structural abnormalities worldwide. Both Methionine synthase reductase (MTRR) and Methionine synthase (MTR) are key enzymes involved in the metabolic p...

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Bibliographic Details
Main Authors: Bingxi Cai, Ti Zhang, Rong Zhong, Li Zou, Beibei Zhu, Wei Chen, Na Shen, Juntao Ke, Jiao Lou, Zhenling Wang, Yu Sun, Lifeng Liu, Ranran Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3942359?pdf=render

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