Positional weight matrices have sufficient prediction power for analysis of noncoding variants [version 2; peer review: 2 approved]
The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software tools in regulatory genomics, including computation...
Main Authors: | Sergey Abramov, Alexandr Boytsov, Vsevolod J. Makeev, Ivan V. Kulakovskiy |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2022-06-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/11-33/v2 |
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