The nucleolus: a paradigm for cell proliferation and aging

The nucleolus: a paradigm for cell proliferation and aging

The nucleolus is the cellular site of ribosome biosynthesis. At this site, active ribosomal DNA (rDNA) genes are rapidly transcribed by RNA polymerase I (pol I) molecules. Recent advances in our understanding of the pol I transcription system have indicated that regulation of ribosomal RNA (rRNA) sy...

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Bibliographic Details
Main Author: Comai L.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
nucleolus
RNA pol I
aging
transcription
Werner syndrome
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200004

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